This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


6cjn

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:28, 13 March 2024) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='6cjn' size='340' side='right'caption='[[6cjn]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='6cjn' size='340' side='right'caption='[[6cjn]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[6cjn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Alfalfa Alfalfa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CJN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CJN FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[6cjn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Medicago_sativa Medicago sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CJN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CJN FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CHI1, CHI-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3879 Alfalfa])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chalcone_isomerase Chalcone isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.5.1.6 5.5.1.6] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cjn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cjn OCA], [https://pdbe.org/6cjn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cjn RCSB], [https://www.ebi.ac.uk/pdbsum/6cjn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cjn ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cjn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cjn OCA], [http://pdbe.org/6cjn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cjn RCSB], [http://www.ebi.ac.uk/pdbsum/6cjn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cjn ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/CFI1_MEDSA CFI1_MEDSA]] Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin.<ref>PMID:10966651</ref> <ref>PMID:11955065</ref> <ref>PMID:11698411</ref>
+
[https://www.uniprot.org/uniprot/CFI1_MEDSA CFI1_MEDSA] Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin.<ref>PMID:10966651</ref> <ref>PMID:11955065</ref> <ref>PMID:11698411</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Alfalfa]]
 
-
[[Category: Chalcone isomerase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Bowman, M E]]
+
[[Category: Medicago sativa]]
-
[[Category: Burke, J R]]
+
[[Category: Bowman ME]]
-
[[Category: Clair, J J.La]]
+
[[Category: Burke JR]]
-
[[Category: Cortina, G]]
+
[[Category: Cortina G]]
-
[[Category: Jez, J M]]
+
[[Category: Jez JM]]
-
[[Category: Kaltenbach, M]]
+
[[Category: Kaltenbach M]]
-
[[Category: Kamerlin, S C.L]]
+
[[Category: Kamerlin SCL]]
-
[[Category: Nelson, A T]]
+
[[Category: La Clair JJ]]
-
[[Category: Noel, J P]]
+
[[Category: Nelson AT]]
-
[[Category: Pabis, A]]
+
[[Category: Noel JP]]
-
[[Category: Philippe, R N]]
+
[[Category: Pabis A]]
-
[[Category: Tawfik, D S]]
+
[[Category: Philippe RN]]
-
[[Category: Woods, K B]]
+
[[Category: Tawfik DS]]
-
[[Category: Flavanone]]
+
[[Category: Woods KB]]
-
[[Category: Isomerase]]
+
-
[[Category: Naringenin]]
+
-
[[Category: Plant protein]]
+

Current revision

Crystal Structure of Chalcone Isomerase from Medicago Sativa with the G95T mutation

PDB ID 6cjn

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools