4g8z

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:41, 14 March 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_4g8z| PDB=4g8z | SCENE= }}
 
-
===pcDHFR K37S/F69N double mutant TMP NADPH ternary complex===
 
-
{{ABSTRACT_PUBMED_23545530}}
 
-
==Function==
+
==pcDHFR K37S/F69N double mutant TMP NADPH ternary complex==
-
[[http://www.uniprot.org/uniprot/DYR_PNECA DYR_PNECA]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
+
<StructureSection load='4g8z' size='340' side='right'caption='[[4g8z]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[4g8z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pneumocystis_jirovecii Pneumocystis jirovecii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G8Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4G8Z FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=TOP:TRIMETHOPRIM'>TOP</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4g8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g8z OCA], [https://pdbe.org/4g8z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4g8z RCSB], [https://www.ebi.ac.uk/pdbsum/4g8z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4g8z ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/DYR_PNECA DYR_PNECA] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
-
==About this Structure==
+
==See Also==
-
[[4g8z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pneumocystis_jirovecii Pneumocystis jirovecii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G8Z OCA].
+
*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:023545530</ref><references group="xtra"/><references/>
+
[[Category: Large Structures]]
-
[[Category: Dihydrofolate reductase]]
+
[[Category: Pneumocystis jirovecii]]
[[Category: Pneumocystis jirovecii]]
-
[[Category: Cody, V.]]
+
[[Category: Cody V]]
-
[[Category: K37s and f69n mutation]]
+
-
[[Category: Mutant pcdhfr inhibitor complex]]
+
-
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
+
-
[[Category: Tmp/nadph ligand]]
+

Current revision

pcDHFR K37S/F69N double mutant TMP NADPH ternary complex

PDB ID 4g8z

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4g8z"
Personal tools