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3nk6
From Proteopedia
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| - | {{STRUCTURE_3nk6| PDB=3nk6 | SCENE= }} | ||
| - | ===Structure of the Nosiheptide-resistance methyltransferase=== | ||
| - | {{ABSTRACT_PUBMED_20550164}} | ||
| - | == | + | ==Structure of the Nosiheptide-resistance methyltransferase== |
| - | [[ | + | <StructureSection load='3nk6' size='340' side='right'caption='[[3nk6]], [[Resolution|resolution]] 2.00Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[3nk6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_actuosus Streptomyces actuosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NK6 FirstGlance]. <br> |
| - | [[3nk6]] is a 2 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nk6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nk6 OCA], [https://pdbe.org/3nk6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nk6 RCSB], [https://www.ebi.ac.uk/pdbsum/3nk6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nk6 ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | < | + | == Function == |
| + | [https://www.uniprot.org/uniprot/NSHR_STRAS NSHR_STRAS] Specifically methylates the adenosine-1067 in 23S ribosomal RNA. Confers resistance to antibiotic nosiheptide.<ref>PMID:20550164</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nk/3nk6_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nk6 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Streptomyces actuosus]] | [[Category: Streptomyces actuosus]] | ||
| - | [[Category: Murchie | + | [[Category: Murchie A]] |
| - | [[Category: Shen | + | [[Category: Shen Y]] |
| - | [[Category: Wang | + | [[Category: Wang P]] |
| - | [[Category: Wang | + | [[Category: Wang Z]] |
| - | [[Category: Xu | + | [[Category: Xu Y]] |
| - | [[Category: Yang | + | [[Category: Yang H]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Structure of the Nosiheptide-resistance methyltransferase
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Categories: Large Structures | Streptomyces actuosus | Murchie A | Shen Y | Wang P | Wang Z | Xu Y | Yang H
