Sulfotransferase

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 5: Line 5:
*'''Heparan sulphate sulfotransferase''' sulfates iduronic acid and glucosamine<ref>PMID:33102470</ref>.
*'''Heparan sulphate sulfotransferase''' sulfates iduronic acid and glucosamine<ref>PMID:33102470</ref>.
*'''Tyrosylprotein sulfotransferase''' performs a post translational protein modification by catalysing the transfer of sulphate to Tyr residues<ref>PMID:9501187</ref>.
*'''Tyrosylprotein sulfotransferase''' performs a post translational protein modification by catalysing the transfer of sulphate to Tyr residues<ref>PMID:9501187</ref>.
-
*'''Sulfotransferase 1A1, 1A2, 1A3''' ar human enzymes which sulfate small planar phenols like neurotransmitters and steroid hormones<ref>PMID:16517757</ref>,<ref>PMID:10762004</ref> .
+
*'''Sulfotransferase 1A1, 1A2''' are human enzymes which sulfate small planar phenols like neurotransmitters and steroid hormones<ref>PMID:16517757</ref>,<ref>PMID:10762004</ref> .
 +
*'''Sulfotransferase 1A3''' is a human enzyme which sulfates dopamine<ref>PMID:17963788</ref>.
== Relevance ==
== Relevance ==

Revision as of 10:21, 14 August 2024

Human estrogen sulfotransferase dimer complex with cofactor PAP, 1hy3

Drag the structure with the mouse to rotate

References

  1. ↑ Malojcic G, Glockshuber R. The PAPS-independent aryl sulfotransferase and the alternative disulfide bond formation system in pathogenic bacteria. Antioxid Redox Signal. 2010 Oct;13(8):1247-59. doi: 10.1089/ars.2010.3119. PMID:20136513 doi:http://dx.doi.org/10.1089/ars.2010.3119
  2. ↑ Yi M, Negishi M, Lee SJ. Estrogen Sulfotransferase (SULT1E1): Its Molecular Regulation, Polymorphisms, and Clinical Perspectives. J Pers Med. 2021 Mar 11;11(3):194. PMID:33799763 doi:10.3390/jpm11030194
  3. ↑ Teixeira FCOB, Vijaya Kumar A, Kumar Katakam S, Cocola C, Pelucchi P, Graf M, Kiesel L, Reinbold R, Pavão MSG, Greve B, Götte M. The Heparan Sulfate Sulfotransferases HS2ST1 and HS3ST2 Are Novel Regulators of Breast Cancer Stem-Cell Properties. Front Cell Dev Biol. 2020 Sep 25;8:559554. PMID:33102470 doi:10.3389/fcell.2020.559554
  4. ↑ Ouyang Yb, Lane WS, Moore KL. Tyrosylprotein sulfotransferase: purification and molecular cloning of an enzyme that catalyzes tyrosine O-sulfation, a common posttranslational modification of eukaryotic proteins. Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):2896-901. PMID:9501187 doi:10.1073/pnas.95.6.2896
  5. ↑ Nagar S, Walther S, Blanchard RL. Sulfotransferase (SULT) 1A1 polymorphic variants *1, *2, and *3 are associated with altered enzymatic activity, cellular phenotype, and protein degradation. Mol Pharmacol. 2006 Jun;69(6):2084-92. PMID:16517757 doi:10.1124/mol.105.019240
  6. ↑ Engelke CE, Meinl W, Boeing H, Glatt H. Association between functional genetic polymorphisms of human sulfotransferases 1A1 and 1A2. Pharmacogenetics. 2000 Mar;10(2):163-9. PMID:10762004 doi:10.1097/00008571-200003000-00008
  7. ↑ Bian HS, Ngo SY, Tan W, Wong CH, Boelsterli UA, Tan TM. Induction of human sulfotransferase 1A3 (SULT1A3) by glucocorticoids. Life Sci. 2007 Dec 14;81(25-26):1659-67. PMID:17963788 doi:10.1016/j.lfs.2007.09.029
  8. ↑ Yalcin EB, More V, Neira KL, Lu ZJ, Cherrington NJ, Slitt AL, King RS. Downregulation of sulfotransferase expression and activity in diseased human livers. Drug Metab Dispos. 2013 Sep;41(9):1642-50. doi: 10.1124/dmd.113.050930. Epub 2013, Jun 17. PMID:23775849 doi:http://dx.doi.org/10.1124/dmd.113.050930
  9. ↑ Pedersen LC, Petrotchenko E, Shevtsov S, Negishi M. Crystal structure of the human estrogen sulfotransferase-PAPS complex: evidence for catalytic role of Ser137 in the sulfuryl transfer reaction. J Biol Chem. 2002 May 17;277(20):17928-32. Epub 2002 Mar 7. PMID:11884392 doi:http://dx.doi.org/10.1074/jbc.M111651200

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/Sulfotransferase"
Personal tools