DNA repair protein
From Proteopedia
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'''DNA repair proteins''' correct DNA damage caused by mutations or toxins<ref>PMID:7773744</ref>. | '''DNA repair proteins''' correct DNA damage caused by mutations or toxins<ref>PMID:7773744</ref>. | ||
*'''DNA repair protein Rad4''' is a yeast protein involved in DNA damage recognition in nucleotide excision repair<ref>PMID:15916602</ref>. Rad4 is an ortholog of the XPC protein. Rad4 opens up damaged DNA by inserting β-hairpin into the duplex and flipping out two damage-containing nucleotide pairs<ref>PMID:27035942</ref>. | *'''DNA repair protein Rad4''' is a yeast protein involved in DNA damage recognition in nucleotide excision repair<ref>PMID:15916602</ref>. Rad4 is an ortholog of the XPC protein. Rad4 opens up damaged DNA by inserting β-hairpin into the duplex and flipping out two damage-containing nucleotide pairs<ref>PMID:27035942</ref>. | ||
| + | *'''DNA repair protein Rev1''' is a DNA polymerase active in DNA damage sites. It contains 2 ubiquitin-binding sites<ref>PMID:29778604</ref>. | ||
| + | *'''DNA repair protein Rad23A, DNA repair protein Rad23B''' see [[UV excision repair protein]]. | ||
| + | *'''DNA repair protein Rad51''' is a multifunctional protein with a role in DNA replication, homologous recombination repair and immunity<ref>PMID:28334891</ref>. | ||
| + | *'''DNA repair protein RadA''' see [[Resolvase]]. | ||
| + | *'''DNA repair protein Xrcc1''' interacts with components of single-strand DNA breaks repair in mammalian cells<ref>PMID:31324530</ref>. | ||
| + | *'''DNA repair protein Xrcc4''' interacts with components of double-strand DNA breaks repair in mammalian cells<ref>PMID:9259561</ref>. | ||
| + | *'''DNA repair protein PprA''' or '''Pleiotropic protein promoting DNA repair A''' facilitates the radiation resistance of ''Deinococcus radiodurans''<ref>PMID:30481062</ref>. | ||
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| + | == Relevance == | ||
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| + | '''DNA repair protein Rad51''' is a potential marker for DNA repair in solid malignancies<ref>PMID:28477336</ref>. | ||
== Disease == | == Disease == | ||
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Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky
