We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

Sandbox Home

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
<table id="tableColumnsMainPage" style="width:100%; border:2px solid #ddd; border-collapse:collapse; table-layout:fixed;">
+
table id="tableColumnsMainPage" style="width:100%;border:2px solid #ddd;border-collapse: collapse;table-layout: fixed; ">
 +
<tr><td colspan='3' style="background:#F5F5FC;border:1px solid #ddd;">
 +
<div style="top:+0.2em; font-size:1.2em; padding:5px 5px 5px 10px; float:right;">'''''ISSN 2310-6301'''''</div>
-
<!-- HEADER -->
+
<span style="border:none; margin:0; padding:0.3em; color:#000; font-style: italic; font-size: 1.4em;">
-
<tr>
+
<b>As life is more than 2D</b>, Proteopedia helps to bridge the gap between 3D structure & function of biomacromolecules
-
<td colspan="3" style="background:#F5F5FC; border:1px solid #ddd;">
+
</span>
-
<div style="position:relative; top:0.2em; font-size:1.2em; padding:5px 5px 5px 10px; float:right;">
+
-
<b><i>ISSN 2310-6301</i></b>
+
-
</div>
+
-
<span style="display:block; margin:0; padding:0.3em; color:#000; font-style:italic; font-size:1.4em;">
+
<span style="border:none; margin:0; padding:0.3em; color:#000; font-style: italic; font-size: 1.1em;max-width:80%;display:block;">
-
<b>As life is more than 2D</b>, Proteopedia helps to bridge the gap between 3D structure &amp; function of biomacromolecules
+
<b>Proteopedia</b> presents this information in a user-friendly way as a '''collaborative & free 3D-encyclopedia of proteins & other biomolecules.'''
-
</span>
+
</span>
-
<span style="display:block; margin:0; padding:0.3em; color:#000; font-style:italic; font-size:1.1em; max-width:80%;">
 
-
<b>Proteopedia</b> presents this information in a user-friendly way as a <b>collaborative &amp; free 3D-encyclopedia of proteins &amp; other biomolecules.</b>
 
-
</span>
 
-
<div style="clear:both;"></div>
+
</td></tr>
-
</td>
+
-
</tr>
+
-
<!-- COLUMN HEADERS -->
+
<tr>
-
<tr>
+
<th style="padding: 10px;background-color: #33ff7b">Selected Research Pages</th>
-
<th style="padding:10px; background-color:#33ff7b;">Selected Research Pages</th>
+
<th style="padding: 10px;background-color: #f1b840">In Journals</th>
-
<th style="padding:10px; background-color:#f1b840;">In Journals</th>
+
<th style="padding: 10px;background-color: #79baff">Education</th>
-
<th style="padding:10px; background-color:#79baff;">Education</th>
+
</tr>
-
</tr>
+
-
<!-- SINGLE CONTENT ROW WITH LINKS AT TOP -->
+
<tr valign='top'>
-
<tr style="vertical-align:top; text-align:center;">
+
<td style="padding: 5px;"> {{Proteopedia:Featured SEL/{{#expr: {{#time:U}} mod {{Proteopedia:Number of SEL articles}}}}}}</td>
-
<!-- LEFT COLUMN -->
+
<td style="padding: 5px;"> {{Proteopedia:Featured JRN/{{#expr: {{#time:U}} mod {{Proteopedia:Number of JRN articles}}}}}}</td>
-
<td style="padding:10px; vertical-align:top;">
+
<td style="padding: 5px;"> {{Proteopedia:Featured EDU/{{#expr: {{#time:U}} mod {{Proteopedia:Number of EDU articles}}}}}}</td>
-
<!-- Links -->
+
</tr>
-
<div>
+
-
<p>[[Help:Contents#For_authors:_contributing_content|How to add content to Proteopedia]]</p>
+
-
<p>[[Proteopedia:Video_Guide|Video Guides]]</p>
+
-
<p>[[Who knows]] ...</p>
+
-
</div>
+
-
<!-- Featured -->
+
-
<div style="margin-top:10px;">
+
-
{{Proteopedia:Featured SEL/{{#expr: {{#time:U}} mod {{Proteopedia:Number of SEL articles}}}}}}
+
-
</div>
+
-
</td>
+
-
<!-- MIDDLE COLUMN -->
+
<tr style="font-size: 1.2em; text-align: center;">
-
<td style="padding:10px; vertical-align:top;">
+
<td style="padding: 10px;background-color: #33ff7b"></td>
-
<div>
+
<td style="padding: 10px;background-color: #f1b840"></td>
-
<p>[[I3DC|About Interactive 3D Complements - '''I3DCs''']]</p>
+
<td style="padding: 10px;background-color: #79baff"></td>
-
<p>[[Proteopedia:I3DC|List of I3DCs]]</p>
+
</tr>
-
<p>[[How to get an I3DC for your paper]]</p>
+
-
</div>
+
-
<div style="margin-top:10px;">
+
-
{{Proteopedia:Featured JRN/{{#expr: {{#time:U}} mod {{Proteopedia:Number of JRN articles}}}}}}
+
-
</div>
+
-
</td>
+
-
<!-- RIGHT COLUMN -->
 
-
<td style="padding:10px; vertical-align:top;">
 
-
<div>
 
-
<p>[[Teaching strategies using Proteopedia]]</p>
 
-
<p>[[Teaching_Scenes%2C_Tutorials%2C_and_Educators%27_Pages|Examples of pages for teaching]]</p>
 
-
<p>[[Help:Contents#For_authors:_contributing_content|How to add content to Proteopedia]]</p>
 
-
</div>
 
-
<div style="margin-top:10px;">
 
-
{{Proteopedia:Featured EDU/{{#expr: {{#time:U}} mod {{Proteopedia:Number of EDU articles}}}}}}
 
-
</div>
 
-
</td>
 
-
</tr>
 
-
<!-- BOTTOM NAV BAR -->
+
<tr style="font-size: 1.0em; text-align: center;">
-
<tr>
+
 
-
<td colspan="3">
+
<td style="padding: 10px;>
-
<table width="100%" style="padding:10px; background-color:#d7d8f9; font-size:1.5em;">
+
<p>[[Help:Contents#For_authors:_contributing_content|How to add content to Proteopedia]]</p>
-
<tr>
+
<p>[[Proteopedia:Video_Guide|Video Guides]]</p>
-
<td>[[Proteopedia:About|About]]</td>
+
<p>[[Who knows]] ...</p>
-
<td>[[Special:Contact|Contact]]</td>
+
</td>
-
<td>[[Template:MainPageNews|Hot News]]</td>
+
 
-
<td>[[Proteopedia:Table of Contents|Table of Contents]]</td>
+
<td style="padding: 10px;>
-
<td>[[Proteopedia:Structure Index|Structure Index]]</td>
+
<p>[[I3DC|About Interactive 3D Complements - '''I3DCs''']]</p>
-
<td>[[Help:Contents|Help]]</td>
+
<p>[[Proteopedia:I3DC|List of I3DCs]]</p>
-
</tr>
+
<p>[[How to get an I3DC for your paper]]</p>
-
</table>
+
 
-
</td>
+
</td>
-
</tr>
+
 
 +
<td style="padding: 10px;>
 +
<p>[[Teaching strategies using Proteopedia]]</p>
 +
<p>[[Teaching_Scenes%2C_Tutorials%2C_and_Educators%27_Pages|Examples of pages for teaching]]</p>
 +
<p>[[Help:Contents#For_authors:_contributing_content|How to add content to Proteopedia]]</p>
 +
</td>
 +
 
 +
</tr>
 +
 
 +
<tr><td colspan='3' >
 +
<table width='100%' style="padding: 10px; background-color: #d7d8f9; font-size: 1.5em;"><tr>
 +
<td>[[Proteopedia:About|About]]</td>
 +
<td>[[Special:Contact|Contact]]</td>
 +
<td>[[Template:MainPageNews|Hot News]]</td>
 +
<td>[[Proteopedia:Table of Contents|Table of Contents]]</td>
 +
<td>[[Proteopedia:Structure Index|Structure Index]]</td>
 +
<td>[[Help:Contents|Help]]</td>
 +
</tr></table>
 +
</td></tr>
</table>
</table>

Revision as of 16:09, 30 September 2025

table id="tableColumnsMainPage" style="width:100%;border:2px solid #ddd;border-collapse: collapse;table-layout: fixed; "> <tr><td colspan='3' style="background:#F5F5FC;border:1px solid #ddd;">

ISSN 2310-6301

As life is more than 2D, Proteopedia helps to bridge the gap between 3D structure & function of biomacromolecules

Proteopedia presents this information in a user-friendly way as a collaborative & free 3D-encyclopedia of proteins & other biomolecules.


</td></tr>

<tr> <th style="padding: 10px;background-color: #33ff7b">Selected Research Pages</th> <th style="padding: 10px;background-color: #f1b840">In Journals</th> <th style="padding: 10px;background-color: #79baff">Education</th> </tr>

<tr valign='top'>

<td style="padding: 5px;">
About this image
Bacteria float with nano-balloons.

ST Huber, D Terwiel, WH Evers, D Maresca, AJ Jakobi. Preprint 2022 doi: 10.1101/2022.05.08.489936
Many kinds of bacteria and archaea control their buoyancy to move to optimal positions in liquid environments. They do this by making nano-compartments called "gas vesicles", long "pipes" with closed ends filled with gases. In 2022, gas vesicle structure was solved, revealing self-assembling thin-walled cylinders of remarkable strength with gas-permeable pores and water-repelling (hydrophobic) interiors. Building on this structural knowledge, gas vesicles are being engineered to serve as biosensors that report via ultrasound.

>>> Visit I3DC Interactive Visualizations >>>

</td> <td style="padding: 5px;">
About this image
Interconversion of the specificities of human lysosomal enzymes associated with Fabry and Schindler diseases.

IB Tomasic, MC Metcalf, AI Guce, NE Clark, SC Garman. J. Biol. Chem. 2010 doi: 10.1074/jbc.M110.118588
The human lysosomal enzymes α-galactosidase and α-N-acetylgalactosaminidase share 46% amino acid sequence identity and have similar folds. Using a rational protein engineering approach, we interconverted the enzymatic specificity of α-GAL and α-NAGAL. The engineered α-GAL retains the antigenicity but has acquired the enzymatic specificity of α-NAGAL. Conversely, the engineered α-NAGAL retains the antigenicity but has acquired the enzymatic specificity of the α-GAL enzyme. Comparison of the crystal structures of the designed enzyme to the wild-type enzymes shows that active sites superimpose well, indicating success of the rational design. The designed enzymes might be useful as non-immunogenic alternatives in enzyme replacement therapy for treatment of lysosomal storage disorders such as Fabry disease.

>>> Visit this I3DC complement >>>

</td> <td style="padding: 5px;">
About this image
Polio is still here!
Polio vaccines have been available since the 1950s, but the challenges of vaccination in remote areas of Afghanistan and Pakistan have prevented worldwide eradication. In 2022, polio was found circulating in parts of New York State, USA. The polio virus has a small RNA genome enclosed in an icosahedral capsid composed of several proteins, shown cut in half. The structures of virus capsids can be explored using free FirstGlance in Jmol.

>>> Visit I3DC Interactive Visualizations >>>

</td>

</tr>

<tr style="font-size: 1.2em; text-align: center;"> <td style="padding: 10px;background-color: #33ff7b"></td> <td style="padding: 10px;background-color: #f1b840"></td> <td style="padding: 10px;background-color: #79baff"></td> </tr>


<tr style="font-size: 1.0em; text-align: center;">

<td style="padding: 10px;>

How to add content to Proteopedia

Video Guides

Who knows ...

</td>

<td style="padding: 10px;>

About Interactive 3D Complements - I3DCs

List of I3DCs

How to get an I3DC for your paper

</td>

<td style="padding: 10px;>

Teaching strategies using Proteopedia

Examples of pages for teaching

How to add content to Proteopedia

</td>

</tr>

<tr><td colspan='3' >

About Contact Hot News Table of Contents Structure Index Help

</td></tr> </table>

Retrieved from "http://52.214.119.220/wiki/index.php/Sandbox_Home"
Personal tools