1bso

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{{STRUCTURE_1bso| PDB=1bso | SCENE= }}
{{STRUCTURE_1bso| PDB=1bso | SCENE= }}
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'''12-BROMODODECANOIC ACID BINDS INSIDE THE CALYX OF BOVINE BETA-LACTOGLOBULIN'''
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===12-BROMODODECANOIC ACID BINDS INSIDE THE CALYX OF BOVINE BETA-LACTOGLOBULIN===
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==Overview==
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The X-ray structure of bovine beta-lactoglobulin with the ligand 12-bromododecanoic acid as a model for fatty acids has been determined at a resolution of 2.23 A in the trigonal lattice Z form. The ligand binds inside the calyx, resolving a long-standing controversy as to where fatty-acid like ligands bind. The carboxylate head group lies at the surface of the molecule, and the lid to the calyx is open at the pH of crystallization (pH 7.3), consistent with the conformation observed in ligand-free bovine beta-lactoglobulin in lattice Z at pH 7.1 and pH 8.2.
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(as it appears on PubMed at http://www.pubmed.gov), where 9827560 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9827560}}
==About this Structure==
==About this Structure==
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[[Category: Ligand binding]]
[[Category: Ligand binding]]
[[Category: X-ray crystal structure]]
[[Category: X-ray crystal structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 11:54:38 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 19:39:47 2008''

Revision as of 16:39, 30 June 2008

Image:1bso.png

Template:STRUCTURE 1bso

12-BROMODODECANOIC ACID BINDS INSIDE THE CALYX OF BOVINE BETA-LACTOGLOBULIN

Template:ABSTRACT PUBMED 9827560

About this Structure

1BSO is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

12-Bromododecanoic acid binds inside the calyx of bovine beta-lactoglobulin., Qin BY, Creamer LK, Baker EN, Jameson GB, FEBS Lett. 1998 Nov 6;438(3):272-8. PMID:9827560

Page seeded by OCA on Mon Jun 30 19:39:47 2008

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