2krk

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{{Seed}}
 
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[[Image:2krk.jpg|left|200px]]
 
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==Solution NMR Structure of 26S protease regulatory subunit 8 from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3102A==
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The line below this paragraph, containing "STRUCTURE_2krk", creates the "Structure Box" on the page.
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<StructureSection load='2krk' size='340' side='right'caption='[[2krk]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2krk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRK FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2krk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krk OCA], [https://pdbe.org/2krk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2krk RCSB], [https://www.ebi.ac.uk/pdbsum/2krk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2krk ProSAT]</span></td></tr>
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{{STRUCTURE_2krk| PDB=2krk | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PRS8_HUMAN PRS8_HUMAN] The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kr/2krk_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2krk ConSurf].
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<div style="clear:both"></div>
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===Solution NMR Structure of 26S protease regulatory subunit 8 from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3102A===
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==See Also==
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*[[Proteasome 3D structures|Proteasome 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2KRK is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRK OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Acton, T B.]]
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[[Category: Large Structures]]
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[[Category: Ciccosanti, C.]]
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[[Category: Acton TB]]
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[[Category: Everett, J K.]]
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[[Category: Ciccosanti C]]
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[[Category: Janjua, J.]]
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[[Category: Everett JK]]
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[[Category: Liu, G.]]
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[[Category: Janjua J]]
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[[Category: Montelione, G T.]]
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[[Category: Liu G]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Montelione GT]]
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[[Category: Nair, R.]]
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[[Category: Nair R]]
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[[Category: Rost, B.]]
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[[Category: Rost B]]
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[[Category: Shastry, R.]]
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[[Category: Shastry R]]
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[[Category: Xiao, R.]]
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[[Category: Xiao R]]
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[[Category: Acetylation]]
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[[Category: Atp-binding]]
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[[Category: Atp-dependent degradation]]
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[[Category: Cytoplasm]]
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[[Category: Nucleotide-binding]]
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[[Category: Nucleus]]
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[[Category: Polymorphism]]
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[[Category: Proteasome]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Structural genomic]]
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[[Category: Target hr3102a]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 13 14:15:42 2010''
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Current revision

Solution NMR Structure of 26S protease regulatory subunit 8 from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3102A

PDB ID 2krk

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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