Pharmaceutical Drug Targets and Diseases
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- | [[Image: Nexium.jpg|300px|right|thumb| AstraZeneca’s Nexium]] | ||
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- | <big>The following is a list of major | + | <big>The following is a list of major pharmaceutical compound targets, drugs, and information organized by disease. </big> |
{{TOC limit|limit=2}} | {{TOC limit|limit=2}} | ||
**Alzheimer’s Disease | **Alzheimer’s Disease | ||
- | ***[[ | + | ***See: [[Alzheimer's Disease]] |
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**Anemia | **Anemia | ||
***[[Erythropoietin]] | ***[[Erythropoietin]] | ||
+ | |||
+ | **Antifungal | ||
+ | ***[[Noxafil]] | ||
+ | |||
+ | **Antimalarial | ||
+ | ***[[Malarial Dihydrofolate Reductase as Drug Target]] | ||
+ | |||
+ | **Anti-parasitic | ||
+ | ***[[Ivermectin|Drug: Ivermectin; Target: Glutamate-gated chloride channels]] | ||
**Asthma and other Pulmonary Disease States | **Asthma and other Pulmonary Disease States | ||
- | ***[[Beta-2 | + | ***[[Beta-2 Adrenergic Receptor]] |
***[[Leukotriene Receptor]] | ***[[Leukotriene Receptor]] | ||
+ | |||
+ | **Atherosclerosis & Hypercholesterolemia | ||
+ | ***[[HMG-CoA Reductase]] | ||
+ | ***[[FLAP|5-Lipoxygenase Activating Protein]] | ||
**Autoimmune Diseases | **Autoimmune Diseases | ||
- | ***[[Tumor Necrosis Factor | + | ***[[Prolyl Endopeptidase]] |
+ | ***[[Tumor necrosis factor receptor]] | ||
+ | ***[[Molecular_Playground/TRAIL|Tumor-Necrosis Factor Apoptosis-Inducing Ligand]] | ||
- | **Blood Clots & Thrombic Events | + | **Bacterial Infections |
+ | *** See: [[Bacterial Infections]] | ||
+ | ***[[Treatment of Tuberculosis]] | ||
+ | |||
+ | **Blood Clots, Haemophilia, & Thrombic Events | ||
***[[P2Y12]] | ***[[P2Y12]] | ||
+ | ***Haemophilia | ||
+ | **** See: [[Hemophilia]] | ||
+ | ***[[Platelet-receptor glycoprotein Ib alpha]] | ||
**Cancer | **Cancer | ||
- | *** | + | *** See: [[Cancer]] |
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**Compromised Immune System | **Compromised Immune System | ||
***[[Granulocyte-macrophage colony-stimulating factor]] | ***[[Granulocyte-macrophage colony-stimulating factor]] | ||
+ | |||
+ | **Delivery Systems & Biotech | ||
+ | ***[[Molecular_Playground/Targeting_Peptide|Targeted Drug Delivery]] | ||
+ | ***[[Monoclonal Antibody]] | ||
**Diabetes & Hypoglycemia | **Diabetes & Hypoglycemia | ||
- | ***[[ | + | *** See: [[Diabetes]] |
**Digestive Diseases | **Digestive Diseases | ||
- | *** | + | ***Proton Pump |
+ | ****[[Esomeprazole and H+/K+ - ATPase Interaction]] | ||
**Erectile Dysfunction | **Erectile Dysfunction | ||
***[[cGMP-Specific Phosphodiesterase Type 5]] | ***[[cGMP-Specific Phosphodiesterase Type 5]] | ||
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- | **HIV | ||
- | ***[[Reverse Transcriptase]] | ||
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- | **Atherosclerosis & Hypercholesterolemia (Elevated Cholesterol) | ||
- | ***[[HMG-CoA Reductase]] | ||
- | ***[[FLAP|5-Lipoxygenase Activating Protein]] | ||
**Hypertension & Congestive Heart Failure | **Hypertension & Congestive Heart Failure | ||
- | ***[[ | + | ***See: [[Hypertension & Congestive Heart Failure]] |
- | + | ||
**Inflammation & Rheumatoid Arthritis | **Inflammation & Rheumatoid Arthritis | ||
- | ***[[ | + | ***[[Inflammation & Rheumatoid Arthritis]] |
- | **Schizophrenia, Bipolar Depression, Insomnia, and Anxiety Disorders | + | **Metabolic Disorders |
- | ***[[Dopamine | + | *** See: [[Metabolic Disorders]] |
- | ***[[ | + | |
- | ***[[Histamine | + | **Schizophrenia, Bipolar Depression, Depression, Insomnia, and Anxiety Disorders |
- | ***[[Opioid | + | ***[[Dopamine receptor]] |
+ | ***[[Adrenergic receptor]] | ||
+ | ***[[Histamine H1 receptor]] | ||
+ | ***[[Opioid receptor]] | ||
+ | ***[[5-hydroxytryptamine receptor]] | ||
+ | |||
+ | **Viral Infection | ||
+ | ***[[Molecular_Playground/T7_RNA_Polymerase_%287_mer_int%29| T7 RNA Polymerase]] | ||
+ | *** HIV | ||
+ | **** See: [[Human Immunodeficiency Virus]] | ||
+ | *** Influenza | ||
+ | **** See: [[Influenza]] | ||
+ | *** [[Herpes Simplex Virus Thymidine Kinase]] | ||
+ | *** [[NS5B|RNA Dependent RNA Polymerase from Hepatitis C Virus]] | ||
+ | *** Poliovirus | ||
+ | ****[[Journal:PLoS ONE:1|Antiviral Activity of 3(2H)- and 6-Chloro-3(2H)-Isoflavenes against Highly Diverged, Neurovirulent Vaccine-Derived, Type2 Poliovirus Sewage Isolates]] | ||
+ | *** [[Interferon]] | ||
}} | }} | ||
+ | |||
+ | See [[Pharmaceutical Drugs]] for descriptions and analysis of well known drugs |
Current revision
The following is a list of major pharmaceutical compound targets, drugs, and information organized by disease.
See Pharmaceutical Drugs for descriptions and analysis of well known drugs
Proteopedia Page Contributors and Editors (what is this?)
David Canner, Alexander Berchansky, Eran Hodis, Thomas J. Stout, Wayne Decatur