Pharmaceutical Drug Targets and Diseases

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[[Image: Nexium.jpg|300px|right|thumb| AstraZeneca’s Nexium]]
 
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<big>The following is a list of major pharmaceutical compound targets, organized by disease. </big>
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<big>The following is a list of major pharmaceutical compound targets, drugs, and information organized by disease. </big>
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**Alzheimer’s Disease
**Alzheimer’s Disease
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***[[Acetylcholinesterase]]
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***See: [[Alzheimer's Disease]]
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***[[Amyloid Beta]]
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***[[Gamma-Secratase]]
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***[[Glutamate receptor (GluA2)]]
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**Anemia
**Anemia
***[[Erythropoietin]]
***[[Erythropoietin]]
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 +
**Antifungal
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***[[Noxafil]]
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**Antimalarial
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***[[Malarial Dihydrofolate Reductase as Drug Target]]
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 +
**Anti-parasitic
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***[[Ivermectin|Drug: Ivermectin; Target: Glutamate-gated chloride channels]]
**Asthma and other Pulmonary Disease States
**Asthma and other Pulmonary Disease States
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***[[Beta-2-Andrenergic Receptor]]
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***[[Beta-2 Adrenergic Receptor]]
***[[Leukotriene Receptor]]
***[[Leukotriene Receptor]]
 +
 +
**Atherosclerosis & Hypercholesterolemia
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***[[HMG-CoA Reductase]]
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***[[FLAP|5-Lipoxygenase Activating Protein]]
**Autoimmune Diseases
**Autoimmune Diseases
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***[[Tumor Necrosis Factor Receptor]]
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***[[Prolyl Endopeptidase]]
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***[[Tumor necrosis factor receptor]]
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***[[Molecular_Playground/TRAIL|Tumor-Necrosis Factor Apoptosis-Inducing Ligand]]
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**Blood Clots & Thrombic Events
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**Bacterial Infections
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*** See: [[Bacterial Infections]]
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***[[Treatment of Tuberculosis]]
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**Blood Clots, Haemophilia, & Thrombic Events
***[[P2Y12]]
***[[P2Y12]]
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***Haemophilia
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**** See: [[Hemophilia]]
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***[[Platelet-receptor glycoprotein Ib alpha]]
**Cancer
**Cancer
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***Growth Factors & Receptors
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*** See: [[Cancer]]
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****Epidermal Growth Factor
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*****[[Epidermal Growth Factor]]
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*****[[Epidermal Growth Factor Receptor]]
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****[[Hepatocyte Growth Factor Receptor]]
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****[[Human Epidermal Growth Factor Receptor 2]]
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****Insulin-Like Growth Factor
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*****[[Insulin-Like Growth Factor-1]]
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*****[[Insulin-Like Growth Factor-1 Receptor]]
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****Vascular Growth Factor
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*****[[Vascular Endothelial Growth Factor]]
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*****[[Vascular Endothelial Growth Factor Receptor]]
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***Kinases
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****[[Cell Division Cycle 7-Related Protein Kinase]]
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****[[Mammalian Target of Rapamycin]]
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****Mitogen-Activated Proteins
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*****Mitogen-Activated Protein Kinase
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*****Mitogen-Activated Protein Kinase Kinase
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*****Mitogen-Activated Protein Kinase Kinase Kinase
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-
******[[c-Raf]]
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****[[Phosphatidylinositol 3-Kinase]]
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-
****[[SRC]]
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***[[Farnesoid X Receptor]]
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-
***[[Heat Shock Protein 90]]
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***[[p53]]
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**Compromised Immune System
**Compromised Immune System
***[[Granulocyte-macrophage colony-stimulating factor]]
***[[Granulocyte-macrophage colony-stimulating factor]]
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 +
**Delivery Systems & Biotech
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***[[Molecular_Playground/Targeting_Peptide|Targeted Drug Delivery]]
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***[[Monoclonal Antibody]]
**Diabetes & Hypoglycemia
**Diabetes & Hypoglycemia
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***[[Peroxisome Proliferator-Activated Receptors]]
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*** See: [[Diabetes]]
**Digestive Diseases
**Digestive Diseases
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***[[Proton Pump]]
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***Proton Pump
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****[[Esomeprazole and H+/K+ - ATPase Interaction]]
**Erectile Dysfunction
**Erectile Dysfunction
***[[cGMP-Specific Phosphodiesterase Type 5]]
***[[cGMP-Specific Phosphodiesterase Type 5]]
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**HIV
 
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***[[Reverse Transcriptase]]
 
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**Atherosclerosis & Hypercholesterolemia (Elevated Cholesterol)
 
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***[[HMG-CoA Reductase]]
 
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***[[FLAP|5-Lipoxygenase Activating Protein]]
 
**Hypertension & Congestive Heart Failure
**Hypertension & Congestive Heart Failure
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***[[Angiotensin-Converting Enzyme]]
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***See: [[Hypertension & Congestive Heart Failure]]
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***[[Calcium Channel]]
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**Inflammation & Rheumatoid Arthritis
**Inflammation & Rheumatoid Arthritis
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***[[Cyclooxygenase]]
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***[[Inflammation & Rheumatoid Arthritis]]
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**Schizophrenia, Bipolar Depression, Insomnia, and Anxiety Disorders
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**Metabolic Disorders
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***[[Dopamine Receptor]]
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*** See: [[Metabolic Disorders]]
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***[[Andrenergic Receptor]]
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***[[Histamine Receptor]]
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**Schizophrenia, Bipolar Depression, Depression, Insomnia, and Anxiety Disorders
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***[[Opioid Receptor]]
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***[[Dopamine receptor]]
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***[[Adrenergic receptor]]
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***[[Histamine H1 receptor]]
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***[[Opioid receptor]]
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***[[5-hydroxytryptamine receptor]]
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**Viral Infection
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***[[Molecular_Playground/T7_RNA_Polymerase_%287_mer_int%29| T7 RNA Polymerase]]
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*** HIV
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**** See: [[Human Immunodeficiency Virus]]
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*** Influenza
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**** See: [[Influenza]]
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*** [[Herpes Simplex Virus Thymidine Kinase]]
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*** [[NS5B|RNA Dependent RNA Polymerase from Hepatitis C Virus]]
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*** Poliovirus
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****[[Journal:PLoS ONE:1|Antiviral Activity of 3(2H)- and 6-Chloro-3(2H)-Isoflavenes against Highly Diverged, Neurovirulent Vaccine-Derived, Type2 Poliovirus Sewage Isolates]]
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*** [[Interferon]]
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See [[Pharmaceutical Drugs]] for descriptions and analysis of well known drugs

Current revision

The following is a list of major pharmaceutical compound targets, drugs, and information organized by disease.

See Pharmaceutical Drugs for descriptions and analysis of well known drugs

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