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Platelet glycoprotein

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[[Image:1m10complexsurf.png|left|350px]]
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<StructureSection load='' size='350' side='right' scene='1m10/Surface/2' caption='Platelet-receptor glycoprotein Ib alpha (blue) involved in Willebrand disease bound to the von Willebrand Factor A1 Domain (green surface), ([[1m10]])' >
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{{Template:1m10SURFACEapplet}}
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{{STRUCTURE_1m10| PDB=1m10 | SCENE= }}
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===Crystal structure of the complex of Glycoprotein Ib alpha and the von Willebrand Factor A1 Domain===
===Crystal structure of the complex of Glycoprotein Ib alpha and the von Willebrand Factor A1 Domain===
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==About this Structure==
==About this Structure==
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{{Button ColorLeucine}} <scene name='1m10/Surface/2'>Initial scene</scene>
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[[1m10]] is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M10 OCA].
[[1m10]] is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M10 OCA].
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==Platelet glycoprotein 4 ==
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'''Platelet glycoprotein 4''' or '''CD36''' functions as a receptor for thrombospondin and collagen <ref>PMID:2665870</ref>.
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</StructureSection>
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==3D structures of platelet glycoprotein==
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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*Platelet glycoprotein Ib
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**[[1gwb]], [[1p9a]], [[1qyy]] – hPGIb von Willenbrand factor binding domain 17-306 - human <BR />
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**[[1m0z]] – hPGIb von Willenbrand factor binding domain (mutant) <BR />
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**[[3rfe]] – hPGIb b chain 26-146<BR />
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**[[3rfe]] – hPGIb b chain 26-146 (mutant)<BR />
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**[[6ejx]] – PGIb a chain von Willenbrand factor binding domain - mouse<BR />
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*Platelet glycoprotein Ib complexes
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**[[1m10]], [[1sq0]] – hPGIb von Willenbrand factor binding domain (mutant) + von Willenbrand factor A1 domain (mutant)<BR />
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**[[6xfq]] – hPGIb von Willenbrand factor binding domain + agkisacucetin<BR />
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**[[1u0n]] – hPGIb von Willenbrand factor binding domain (mutant) + von Willenbrand factor A1 domain + botrocetin<BR />
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**[[3pmh]], [[1gwb]] – hPGIb von Willenbrand factor binding domain (mutant) + thrombin<BR />
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**[[1p8v]] – hPGIb von Willenbrand factor binding domain (mutant) + prothrombin<BR />
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**[[1sq0]] – hPGIb von Willenbrand factor binding domain + peptide inhibitor<BR />
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**[[2bp3]] – hPGIb cytoplasmic domain + filamin A rod domain <BR />
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**[[1ook]] – hPGIb a chain + alpha thrombin + peptide<BR />
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**[[4c2a]], [[4c2b]] – hPGIb a chain (mutant) + von Willenbrand factor <BR />
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**[[3p72]] – hPGIb a chain + peptide inhibitor<BR />
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*Platelet glycoprotein 4
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**[[5lgd]] – hPG4 + PFEMP1 <BR />
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*Platelet glycoprotein 6
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**[[2gi7]], [5ou7]] – hPG6 <BR />
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**[[5ou9]], [[5ou8]] – hPG6 + collagen peptide <BR />
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**[[7nmu]] – hPG6 + nanobody <BR />
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**[[7r58]] – hPG6 + antibody <BR />
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}}
==Reference==
==Reference==
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==See Also==
==See Also==
*[[Leucine-rich repeat]]
*[[Leucine-rich repeat]]
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*[[Variable Lymphocyte Receptors]]
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*[[Variable lymphocyte receptor]]
*[[Lamprey Variable Lymphocyte Receptor]]
*[[Lamprey Variable Lymphocyte Receptor]]
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*[[Disease]]
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*[[Diseases]]
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[[Category:Topic Page]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Groot, P G.de.]]
[[Category: Groot, P G.de.]]

Current revision

Platelet-receptor glycoprotein Ib alpha (blue) involved in Willebrand disease bound to the von Willebrand Factor A1 Domain (green surface), (1m10)

Drag the structure with the mouse to rotate

3D structures of platelet glycoprotein

Updated on 03-September-2023

Reference

  • Huizinga EG, Tsuji S, Romijn RA, Schiphorst ME, de Groot PG, Sixma JJ, Gros P. Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain. Science. 2002 Aug 16;297(5584):1176-9. PMID:12183630 doi:10.1126/science.107355

See Also

Retrieved from "http://52.214.119.220/wiki/index.php/Platelet_glycoprotein"
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