Multi-protein assemblies
From Proteopedia
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Many [[PDB file|PDB files]] contain [[Complexes|complexes]] in which a particular protein is interacting with a different protein in what are called [[Multi-protein assemblies|multi-protein assemblies]] or [[Multi-protein assemblies|multi-protein complexes]]. These interactions, if biologically relevant, can be immensely insightful in shedding light on cellular and extracellular processes. | Many [[PDB file|PDB files]] contain [[Complexes|complexes]] in which a particular protein is interacting with a different protein in what are called [[Multi-protein assemblies|multi-protein assemblies]] or [[Multi-protein assemblies|multi-protein complexes]]. These interactions, if biologically relevant, can be immensely insightful in shedding light on cellular and extracellular processes. | ||
| - | ==See Also== | ||
| - | *[[Crystal contacts]] | ||
| - | *[[X-ray crystallography]] | ||
| - | *[[Biological assembly]] | ||
==Examples== | ==Examples== | ||
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* [[Platelet-receptor glycoprotein Ib alpha|Platelet-receptor glycoprotein Ib alpha bound to the von Willebrand Factor A1 Domain]] | * [[Platelet-receptor glycoprotein Ib alpha|Platelet-receptor glycoprotein Ib alpha bound to the von Willebrand Factor A1 Domain]] | ||
| - | ==Web Sites== | ||
| - | *[http://www-cryst.bioc.cam.ac.uk/~richard/piccolo/about.php PICCOLO, a comprehensive relational database featuring the details of structurally characterized protein-protein interactions]. | ||
| - | == | + | ==See Also== |
| + | * [[Complexes]] | ||
| + | * [[Complexes|Assemblies]] | ||
| + | * [[Biological assembly|Biological unit]] | ||
| + | * [[Biological assembly]] | ||
| + | * [[Crystal contacts]] | ||
| + | * [[X-ray crystallography]] | ||
| + | * [[Ligand]] | ||
| - | Literature citations | + | |
| + | ==External Resources== | ||
| + | * [http://www-cryst.bioc.cam.ac.uk/~richard/piccolo/about.php PICCOLO, a comprehensive relational database featuring the details of structurally characterized protein-protein interactions]. | ||
| + | * [http://pir.georgetown.edu/pro/ PRO] provides an ontological representation of proteins in complexes. In particular, the authors are working to implement logical and consistent representation of protein complexes. | ||
| + | *[https://www.molnac.unisa.it/BioTools/cocomaps/ COCOMAPS (bioCOmplexes COntact MAPS)] is a web server for analysis and visualization of the interfaces present in biological complexes, such as protein-protein, protein-DNA and protein-RNA complexes, making use of intermolecular contact maps. | ||
| + | * [http://haddock.chem.uu.nl/ The HADDOCK web server] is web server for data-driven biomolecular docking for modeling of biomolecular complexes. | ||
| + | |||
| + | ==Literature Citations== | ||
| + | Literature citations can also be found at the respective servers linked above. | ||
Current revision
Many PDB files contain complexes in which a particular protein is interacting with a different protein in what are called multi-protein assemblies or multi-protein complexes. These interactions, if biologically relevant, can be immensely insightful in shedding light on cellular and extracellular processes.
Contents |
Examples
- Ribosome
- Human Follicle-Stimulating Hormone Complexed with its Receptor
- Platelet-receptor glycoprotein Ib alpha bound to the von Willebrand Factor A1 Domain
See Also
- Complexes
- Assemblies
- Biological unit
- Biological assembly
- Crystal contacts
- X-ray crystallography
- Ligand
External Resources
- PICCOLO, a comprehensive relational database featuring the details of structurally characterized protein-protein interactions.
- PRO provides an ontological representation of proteins in complexes. In particular, the authors are working to implement logical and consistent representation of protein complexes.
- COCOMAPS (bioCOmplexes COntact MAPS) is a web server for analysis and visualization of the interfaces present in biological complexes, such as protein-protein, protein-DNA and protein-RNA complexes, making use of intermolecular contact maps.
- The HADDOCK web server is web server for data-driven biomolecular docking for modeling of biomolecular complexes.
Literature Citations
Literature citations can also be found at the respective servers linked above.
