3ozb

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[[Image:3ozb.jpg|left|200px]]
 
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==Crystal Structure of 5'-methylthioinosine phosphorylase from Psedomonas aeruginosa in complex with hypoxanthine==
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The line below this paragraph, containing "STRUCTURE_3ozb", creates the "Structure Box" on the page.
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<StructureSection load='3ozb' size='340' side='right'caption='[[3ozb]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ozb]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OZB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OZB FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HPA:HYPOXANTHINE'>HPA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3ozb| PDB=3ozb | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ozb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ozb OCA], [https://pdbe.org/3ozb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ozb RCSB], [https://www.ebi.ac.uk/pdbsum/3ozb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ozb ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of 5'-methylthioinosine phosphorylase from Psedomonas aeruginosa in complex with hypoxanthine===
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== Function ==
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[https://www.uniprot.org/uniprot/MTIP_PSEAE MTIP_PSEAE] Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. Involved in quorum sensing.[HAMAP-Rule:MF_01963]<ref>PMID:21197954</ref>
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 21197954 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_21197954}}
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Almo SC]]
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==About this Structure==
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[[Category: Guan R]]
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[[3ozb]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OZB OCA].
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[[Category: Ho M]]
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[[Category: Schramm VL]]
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==Reference==
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<ref group="xtra">PMID:021197954</ref><references group="xtra"/>
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[[Category: Pseudomonas aeruginosa]]
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[[Category: S-methyl-5'-thioadenosine phosphorylase]]
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[[Category: Almo, S C.]]
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[[Category: Guan, R.]]
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[[Category: Ho, M.]]
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[[Category: Schramm, V L.]]
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[[Category: 5'-methylthioinosine]]
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[[Category: Phosphorylase]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of 5'-methylthioinosine phosphorylase from Psedomonas aeruginosa in complex with hypoxanthine

PDB ID 3ozb

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