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3v69

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[[Image:3v69.jpg|left|200px]]
 
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==Filia-N crystal structure==
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The line below this paragraph, containing "STRUCTURE_3v69", creates the "Structure Box" on the page.
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<StructureSection load='3v69' size='340' side='right'caption='[[3v69]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3v69]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V69 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V69 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v69 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v69 OCA], [https://pdbe.org/3v69 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v69 RCSB], [https://www.ebi.ac.uk/pdbsum/3v69 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v69 ProSAT]</span></td></tr>
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{{STRUCTURE_3v69| PDB=3v69 | SCENE= }}
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</table>
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== Function ==
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===Filia-N crystal structure===
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[https://www.uniprot.org/uniprot/KHDC3_MOUSE KHDC3_MOUSE] Required for maintenance of euploidy during cleavage-stage embryogenesis. Ensures proper spindle assembly by regulating the localization of AURKA via RHOA signaling and of PLK1 via a RHOA-independent process. Required for the localization of MAD2L1 to kinetochores to enable spindle assembly checkpoint function. Capable of binding RNA.<ref>PMID:19376971</ref> <ref>PMID:22276159</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 22276159 is the PubMed ID number.
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_22276159}}
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==About this Structure==
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[[3v69]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V69 OCA].
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==Reference==
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<ref group="xtra">PMID:022276159</ref><references group="xtra"/>
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Li, L.]]
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[[Category: Li L]]
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[[Category: Liu, X.]]
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[[Category: Liu X]]
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[[Category: Wang, J.]]
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[[Category: Wang J]]
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[[Category: Xu, M.]]
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[[Category: Xu M]]
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[[Category: Zhu, K.]]
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[[Category: Zhu K]]
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[[Category: Embryogenesis]]
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[[Category: Filia]]
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[[Category: Kh domain]]
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[[Category: Protein binding]]
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[[Category: Rna binding]]
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[[Category: Rna-binding]]
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Current revision

Filia-N crystal structure

PDB ID 3v69

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OCA

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