4af8

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[[Image:4af8.png|left|200px]]
 
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==The structural basis for metacaspase substrate specificity and activation==
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The line below this paragraph, containing "STRUCTURE_4af8", creates the "Structure Box" on the page.
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<StructureSection load='4af8' size='340' side='right'caption='[[4af8]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[4af8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AF8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AF8 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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{{STRUCTURE_4af8| PDB=4af8 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4af8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4af8 OCA], [https://pdbe.org/4af8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4af8 RCSB], [https://www.ebi.ac.uk/pdbsum/4af8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4af8 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MCA2_TRYB2 MCA2_TRYB2] Cysteine protease that cleaves specifically after arginine or lysine residues.<ref>PMID:18005666</ref> <ref>PMID:23506317</ref>
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===The structural basis for metacaspase substrate specificity and activation===
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==See Also==
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*[[Caspase 3D structures|Caspase 3D structures]]
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 22529389 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_22529389}}
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==About this Structure==
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[[4af8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AF8 OCA].
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==Reference==
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<ref group="xtra">PMID:022529389</ref><references group="xtra"/>
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[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
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[[Category: Coombs, G H.]]
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[[Category: Coombs GH]]
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[[Category: Isaacs, N W.]]
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[[Category: Isaacs NW]]
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[[Category: Mcluskey, K.]]
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[[Category: McLuskey K]]
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[[Category: Moss, C X.]]
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[[Category: Moss CX]]
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[[Category: Mottram, J C.]]
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[[Category: Mottram JC]]
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[[Category: Rudolf, J.]]
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[[Category: Rudolf J]]
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[[Category: Caspase/hemoglobin fold]]
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[[Category: Cysteine peptidase]]
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[[Category: Hydrolase]]
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Current revision

The structural basis for metacaspase substrate specificity and activation

PDB ID 4af8

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OCA

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