2krk
From Proteopedia
(Difference between revisions)
| (7 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2krk.png|left|200px]] | ||
| - | + | ==Solution NMR Structure of 26S protease regulatory subunit 8 from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3102A== | |
| - | + | <StructureSection load='2krk' size='340' side='right'caption='[[2krk]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2krk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2krk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krk OCA], [https://pdbe.org/2krk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2krk RCSB], [https://www.ebi.ac.uk/pdbsum/2krk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2krk ProSAT]</span></td></tr> |
| - | [[2krk]] is a 1 chain structure with sequence from [ | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PRS8_HUMAN PRS8_HUMAN] The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kr/2krk_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2krk ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Proteasome|Proteasome]] | + | *[[Proteasome 3D structures|Proteasome 3D structures]] |
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Acton | + | [[Category: Large Structures]] |
| - | [[Category: Ciccosanti | + | [[Category: Acton TB]] |
| - | [[Category: Everett | + | [[Category: Ciccosanti C]] |
| - | [[Category: Janjua | + | [[Category: Everett JK]] |
| - | [[Category: Liu | + | [[Category: Janjua J]] |
| - | [[Category: Montelione | + | [[Category: Liu G]] |
| - | + | [[Category: Montelione GT]] | |
| - | [[Category: Nair | + | [[Category: Nair R]] |
| - | [[Category: Rost | + | [[Category: Rost B]] |
| - | [[Category: Shastry | + | [[Category: Shastry R]] |
| - | [[Category: Xiao | + | [[Category: Xiao R]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Solution NMR Structure of 26S protease regulatory subunit 8 from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3102A
| |||||||||||
Categories: Homo sapiens | Large Structures | Acton TB | Ciccosanti C | Everett JK | Janjua J | Liu G | Montelione GT | Nair R | Rost B | Shastry R | Xiao R
