3df6
From Proteopedia
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| - | [[Image:3df6.png|left|200px]] | ||
| - | + | ==The thermo- and acido-stable ORF-99 from the archaeal virus AFV1== | |
| + | <StructureSection load='3df6' size='340' side='right'caption='[[3df6]], [[Resolution|resolution]] 2.05Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3df6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Acidianus_filamentous_virus_1 Acidianus filamentous virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DF6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DF6 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3df6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3df6 OCA], [https://pdbe.org/3df6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3df6 RCSB], [https://www.ebi.ac.uk/pdbsum/3df6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3df6 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Y099_AFV1Y Y099_AFV1Y] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Acidianus Filamentous Virus 1 (AFV1), isolated from acidic hot springs, is an enveloped lipid-containing archaeal filamentous virus with a linear double-stranded DNA genome. It infects Acidianus, which is a hyperthermostable archaea growing at 85 degrees C and acidic pHs, below pH 3. AFV1-99, a protein of 99 amino acids of unknown function, has homologues in the archaeal virus families Lipothrixviridae and Rudiviridae. We determined the crystal structure of AFV1-99 at 2.05 A resolution. AFV1-99 has a new fold, is hyperthermostable (up to 95 degrees C) and resists to extreme pH (between pH 0 and 11) and to the combination of high temperature (95 degrees C) and low pH (pH 0). It possesses characteristics of hyperthermostable proteins, such as a high content of charged residues. | ||
| - | + | The thermo- and acido-stable ORF-99 from the archaeal virus AFV1.,Goulet A, Spinelli S, Blangy S, van Tilbeurgh H, Leulliot N, Basta T, Prangishvili D, Cambillau C, Campanacci V Protein Sci. 2009 Jun;18(6):1316-20. PMID:19472363<ref>PMID:19472363</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | <div class="pdbe-citations 3df6" style="background-color:#fffaf0;"></div> | |
| - | + | == References == | |
| - | + | <references/> | |
| - | == | + | __TOC__ |
| - | < | + | </StructureSection> |
[[Category: Acidianus filamentous virus 1]] | [[Category: Acidianus filamentous virus 1]] | ||
| - | [[Category: Cambillau | + | [[Category: Large Structures]] |
| - | [[Category: Campanacci | + | [[Category: Cambillau C]] |
| - | [[Category: Goulet | + | [[Category: Campanacci V]] |
| - | [[Category: Prangishvili | + | [[Category: Goulet A]] |
| - | [[Category: Spinelli | + | [[Category: Prangishvili D]] |
| - | [[Category: Tilbeurgh | + | [[Category: Spinelli S]] |
| - | + | [[Category: Van Tilbeurgh H]] | |
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Current revision
The thermo- and acido-stable ORF-99 from the archaeal virus AFV1
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