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3unb
From Proteopedia
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| - | {{Large structure}} | ||
| - | {{STRUCTURE_3unb| PDB=3unb | SCENE= }} | ||
| - | ===Mouse constitutive 20S proteasome in complex with PR-957=== | ||
| - | {{ABSTRACT_PUBMED_22341445}} | ||
| - | == | + | ==Mouse constitutive 20S proteasome in complex with PR-957== |
| - | [[3unb]] is a | + | <StructureSection load='3unb' size='340' side='right'caption='[[3unb]], [[Resolution|resolution]] 2.90Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3unb]] is a 40 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UNB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UNB FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=04C:1,2,4-TRIDEOXY-4-METHYL-2-{[N-(MORPHOLIN-4-YLACETYL)-L-ALANYL-O-METHYL-L-TYROSYL]AMINO}-1-PHENYL-D-XYLITOL'>04C</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3unb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3unb OCA], [https://pdbe.org/3unb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3unb RCSB], [https://www.ebi.ac.uk/pdbsum/3unb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3unb ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PSA2_MOUSE PSA2_MOUSE] The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. PSMA2 may have a potential regulatory effect on another component(s) of the proteasome complex through tyrosine phosphorylation. | ||
==See Also== | ==See Also== | ||
*[[Proteasome|Proteasome]] | *[[Proteasome|Proteasome]] | ||
| - | + | *[[Proteasome 3D structures|Proteasome 3D structures]] | |
| - | + | __TOC__ | |
| - | < | + | </StructureSection> |
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Basler | + | [[Category: Basler M]] |
| - | [[Category: Groettrup | + | [[Category: Groettrup M]] |
| - | [[Category: Groll | + | [[Category: Groll M]] |
| - | [[Category: Heinemeyer | + | [[Category: Heinemeyer W]] |
| - | [[Category: Huber | + | [[Category: Huber E]] |
| - | [[Category: Kirk | + | [[Category: Kirk C]] |
| - | [[Category: Schwab | + | [[Category: Schwab R]] |
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Current revision
Mouse constitutive 20S proteasome in complex with PR-957
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Categories: Large Structures | Mus musculus | Basler M | Groettrup M | Groll M | Heinemeyer W | Huber E | Kirk C | Schwab R
