2kr0

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{{Large structure}}
 
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{{STRUCTURE_2kr0| PDB=2kr0 | SCENE= }}
 
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===A proteasome protein===
 
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{{ABSTRACT_PUBMED_20471946}}
 
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==About this Structure==
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==Solution structure of the proteasome ubiquitin receptor Rpn13==
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[[2kr0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KR0 OCA].
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<StructureSection load='2kr0' size='340' side='right'caption='[[2kr0]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2kr0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KR0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KR0 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kr0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kr0 OCA], [https://pdbe.org/2kr0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kr0 RCSB], [https://www.ebi.ac.uk/pdbsum/2kr0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kr0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ADRM1_HUMAN ADRM1_HUMAN] Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity.<ref>PMID:16990800</ref> <ref>PMID:17139257</ref> <ref>PMID:16815440</ref> <ref>PMID:16906146</ref> <ref>PMID:18497817</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kr/2kr0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kr0 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Proteasome|Proteasome]]
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*[[Proteasome 3D structures|Proteasome 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:020471946</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Chen, X.]]
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[[Category: Large Structures]]
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[[Category: Finley, D.]]
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[[Category: Chen X]]
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[[Category: Lee, B.]]
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[[Category: Finley D]]
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[[Category: Walters, K J.]]
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[[Category: Lee B]]
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[[Category: 19s regulator]]
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[[Category: Walters KJ]]
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[[Category: Proteasome]]
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[[Category: Protein binding]]
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[[Category: Ubiquitin]]
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Current revision

Solution structure of the proteasome ubiquitin receptor Rpn13

PDB ID 2kr0

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OCA

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