3nk6

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{{STRUCTURE_3nk6| PDB=3nk6 | SCENE= }}
 
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===Structure of the Nosiheptide-resistance methyltransferase===
 
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{{ABSTRACT_PUBMED_20550164}}
 
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==Function==
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==Structure of the Nosiheptide-resistance methyltransferase==
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[[http://www.uniprot.org/uniprot/NHS_STRAS NHS_STRAS]] Confers resistance to antibiotic nosiheptide.
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<StructureSection load='3nk6' size='340' side='right'caption='[[3nk6]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[3nk6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_actuosus Streptomyces actuosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NK6 FirstGlance]. <br>
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[[3nk6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_actuosus Streptomyces actuosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK6 OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nk6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nk6 OCA], [https://pdbe.org/3nk6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nk6 RCSB], [https://www.ebi.ac.uk/pdbsum/3nk6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nk6 ProSAT]</span></td></tr>
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==Reference==
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</table>
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<ref group="xtra">PMID:020550164</ref><references group="xtra"/><references/>
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== Function ==
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[https://www.uniprot.org/uniprot/NSHR_STRAS NSHR_STRAS] Specifically methylates the adenosine-1067 in 23S ribosomal RNA. Confers resistance to antibiotic nosiheptide.<ref>PMID:20550164</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nk/3nk6_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nk6 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Streptomyces actuosus]]
[[Category: Streptomyces actuosus]]
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[[Category: Murchie, A.]]
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[[Category: Murchie A]]
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[[Category: Shen, Y.]]
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[[Category: Shen Y]]
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[[Category: Wang, P.]]
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[[Category: Wang P]]
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[[Category: Wang, Z.]]
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[[Category: Wang Z]]
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[[Category: Xu, Y.]]
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[[Category: Xu Y]]
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[[Category: Yang, H.]]
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[[Category: Yang H]]
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[[Category: 23s rrna methyltransferase]]
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[[Category: Nosiheptide]]
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[[Category: Nosiheptide-resistance methyltransferase]]
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[[Category: Transferase]]
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Current revision

Structure of the Nosiheptide-resistance methyltransferase

PDB ID 3nk6

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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