3j47

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{{STRUCTURE_3j47| PDB=3j47 | SCENE= }}
 
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===Formation of an intricate helical bundle dictates the assembly of the 26S proteasome lid===
 
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{{ABSTRACT_PUBMED_22927375}}
 
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==Function==
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==Formation of an intricate helical bundle dictates the assembly of the 26S proteasome lid==
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[[http://www.uniprot.org/uniprot/RPN7_YEAST RPN7_YEAST]] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (By similarity). [[http://www.uniprot.org/uniprot/RPN9_YEAST RPN9_YEAST]] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. [[http://www.uniprot.org/uniprot/RPN3_YEAST RPN3_YEAST]] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. [[http://www.uniprot.org/uniprot/RPN8_YEAST RPN8_YEAST]] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.<ref>PMID:9584156</ref> [[http://www.uniprot.org/uniprot/RPN12_YEAST RPN12_YEAST]] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Necessary for activation of the CDC28 kinase. [[http://www.uniprot.org/uniprot/RPN11_YEAST RPN11_YEAST]] Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.<ref>PMID:21075847</ref> [[http://www.uniprot.org/uniprot/RPN5_YEAST RPN5_YEAST]] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.<ref>PMID:9426256</ref> [[http://www.uniprot.org/uniprot/RPN6_YEAST RPN6_YEAST]] Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, RPN6 is required for proteasome assembly.<ref>PMID:9426256</ref> <ref>PMID:12486135</ref> <ref>PMID:15611133</ref>
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<SX load='3j47' size='340' side='right' viewer='molstar' caption='[[3j47]], [[Resolution|resolution]] 7.40&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3j47]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J47 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J47 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j47 OCA], [https://pdbe.org/3j47 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j47 RCSB], [https://www.ebi.ac.uk/pdbsum/3j47 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j47 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RPN11_YEAST RPN11_YEAST] Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.<ref>PMID:21075847</ref>
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==About this Structure==
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==See Also==
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[[3j47]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J47 OCA].
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*[[Proteasome 3D structures|Proteasome 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:022927375</ref><references group="xtra"/><references/>
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__TOC__
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[[Category: Saccharomyces cerevisiae]]
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</SX>
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[[Category: Chacon, P.]]
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[[Category: Large Structures]]
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[[Category: Estrin, E.]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Lopez-Blanco, J R.]]
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[[Category: Chacon P]]
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[[Category: Martin, A.]]
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[[Category: Estrin E]]
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[[Category: Alpha helix bundle]]
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[[Category: Lopez-Blanco JR]]
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[[Category: Flexible fitting]]
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[[Category: Martin A]]
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[[Category: Hybrid method]]
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[[Category: Protein binding]]
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Current revision

Formation of an intricate helical bundle dictates the assembly of the 26S proteasome lid

3j47, resolution 7.40Å

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