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4mj8
From Proteopedia
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| - | {{STRUCTURE_4mj8| PDB=4mj8 | SCENE= }} | ||
| - | ===Crystal structure of spermidine N-acetyltransferase from Vibrio cholerae in complex with polyamine in substrate binding site=== | ||
| - | == | + | ==Crystal structure of spermidine N-acetyltransferase from Vibrio cholerae in complex with polyamine== |
| - | [[4mj8]] is a 3 chain structure with sequence from [ | + | <StructureSection load='4mj8' size='340' side='right'caption='[[4mj8]], [[Resolution|resolution]] 2.04Å' scene=''> |
| - | [ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[4mj8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae_O1_biovar_El_Tor_str._N16961 Vibrio cholerae O1 biovar El Tor str. N16961]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MJ8 FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04Å</td></tr> |
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mj8 OCA], [https://pdbe.org/4mj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mj8 RCSB], [https://www.ebi.ac.uk/pdbsum/4mj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mj8 ProSAT]</span></td></tr> | |
| - | [ | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/ATDA_VIBCH ATDA_VIBCH] Involved in the protection against polyamine toxicity by regulating their concentration. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to the primary amino groups of spermidine to yield N(1)- and N(8)-acetylspermidine. It can use polyamines such as spermine and N(1)-acetylspermine, but not putrescine or cadaverine.<ref>PMID:23184347</ref> <ref>PMID:25623305</ref> |
| - | [[Category: | + | |
| - | [[Category: | + | ==See Also== |
| - | [[Category: | + | *[[Spermidine/spermine N-acetyltransferase|Spermidine/spermine N-acetyltransferase]] |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Vibrio cholerae O1 biovar El Tor str. N16961]] | ||
| + | [[Category: Anderson WF]] | ||
| + | [[Category: Filippova EV]] | ||
| + | [[Category: Kiryukhina O]] | ||
| + | [[Category: Kuhn ML]] | ||
| + | [[Category: Minasov G]] | ||
| + | [[Category: Shuvalova L]] | ||
Current revision
Crystal structure of spermidine N-acetyltransferase from Vibrio cholerae in complex with polyamine
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