4nnw
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4nnw is ON HOLD Authors: Stein, M.L., Cui, H., Beck, P., Dubiella, C., Voss, C., Krueger, A., Schmidt, B., Groll, M. Description: yCP in complex wi...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==yCP in complex with Z-Leu-Leu-Leu-ketoaldehyde== | |
| + | <StructureSection load='4nnw' size='340' side='right'caption='[[4nnw]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4nnw]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NNW FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2MK:N-[(BENZYLOXY)CARBONYL]-L-LEUCYL-N-[(2R,3S)-1,2-DIHYDROXY-5-METHYLHEXAN-3-YL]-L-LEUCINAMIDE'>2MK</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nnw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nnw OCA], [https://pdbe.org/4nnw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nnw RCSB], [https://www.ebi.ac.uk/pdbsum/4nnw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nnw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PSA2_YEAST PSA2_YEAST] The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity. | ||
| - | + | ==See Also== | |
| - | + | *[[Proteasome 3D structures|Proteasome 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Beck P]] | ||
| + | [[Category: Cui H]] | ||
| + | [[Category: Dubiella C]] | ||
| + | [[Category: Groll M]] | ||
| + | [[Category: Krueger A]] | ||
| + | [[Category: Schmidt B]] | ||
| + | [[Category: Stein ML]] | ||
| + | [[Category: Voss C]] | ||
Current revision
yCP in complex with Z-Leu-Leu-Leu-ketoaldehyde
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Categories: Large Structures | Saccharomyces cerevisiae S288C | Beck P | Cui H | Dubiella C | Groll M | Krueger A | Schmidt B | Stein ML | Voss C
