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2yxy

From Proteopedia

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[[Image:2yxy.gif|left|200px]]<br /><applet load="2yxy" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2yxy, resolution 2.20&Aring;" />
 
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'''Crystarl structure of Hypothetical conserved protein, GK0453'''<br />
 
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==About this Structure==
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==Crystarl structure of Hypothetical conserved protein, GK0453==
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2YXY is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Geobacillus_kaustophilus Geobacillus kaustophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXY OCA].
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<StructureSection load='2yxy' size='340' side='right'caption='[[2yxy]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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[[Category: Geobacillus kaustophilus]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[2yxy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_kaustophilus_HTA426 Geobacillus kaustophilus HTA426]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YXY FirstGlance]. <br>
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[[Category: Bessho, Y.]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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[[Category: Nakamu, Y.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yxy OCA], [https://pdbe.org/2yxy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yxy RCSB], [https://www.ebi.ac.uk/pdbsum/2yxy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yxy ProSAT], [https://www.topsan.org/Proteins/RSGI/2yxy TOPSAN]</span></td></tr>
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[[Category: Padmanabhan, B.]]
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</table>
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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== Function ==
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[[Category: Yokoyama, S.]]
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[https://www.uniprot.org/uniprot/Q5L2U2_GEOKA Q5L2U2_GEOKA]
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[[Category: alpha and beta proteins (a+b) class]]
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== Evolutionary Conservation ==
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[[Category: gk0453]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: national project on protein structural and functional analyses]]
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Check<jmol>
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[[Category: nppsfa]]
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<jmolCheckbox>
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[[Category: riken structural genomics/proteomics initiative]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yx/2yxy_consurf.spt"</scriptWhenChecked>
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[[Category: rsgi]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: structural genomics]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: unknown function]]
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yxy ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The crystal structure of a conserved hypothetical protein, GK0453, from Geobacillus kaustophilus has been determined to 2.2 A resolution. The crystal belonged to space group P43212, with unit-cell parameters a = b = 75.69, c = 64.18 A. The structure was determined by the molecular-replacement method and was refined to a final R factor of 22.6% (Rfree = 26.3%). Based on structural homology, the GK0453 protein possesses two independent binding sites and hence it may simultaneously interact with two proteins or with a protein and a nucleic acid.
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:58:40 2008''
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Structure of the hypothetical DUF1811-family protein GK0453 from Geobacillus kaustophilus HTA426.,Padmanabhan B, Nakamura Y, Antonyuk SV, Strange RW, Hasnain SS, Yokoyama S, Bessho Y Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Apr 1;69(Pt 4):342-5. doi:, 10.1107/S1744309113003369. Epub 2013 Mar 28. PMID:23545635<ref>PMID:23545635</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 2yxy" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Geobacillus kaustophilus HTA426]]
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[[Category: Large Structures]]
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[[Category: Bessho Y]]
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[[Category: Nakamu Y]]
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[[Category: Padmanabhan B]]
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[[Category: Yokoyama S]]

Current revision

Crystarl structure of Hypothetical conserved protein, GK0453

PDB ID 2yxy

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