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4quv

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==Structure of an integral membrane delta(14)-sterol reductase==
==Structure of an integral membrane delta(14)-sterol reductase==
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<StructureSection load='4quv' size='340' side='right' caption='[[4quv]], [[Resolution|resolution]] 2.74&Aring;' scene=''>
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<StructureSection load='4quv' size='340' side='right'caption='[[4quv]], [[Resolution|resolution]] 2.74&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4quv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QUV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QUV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4quv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methylotuvimicrobium_alcaliphilum_20Z Methylotuvimicrobium alcaliphilum 20Z]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QUV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QUV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.743&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Delta(14)-sterol_reductase Delta(14)-sterol reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.70 1.3.1.70] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4quv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4quv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4quv RCSB], [http://www.ebi.ac.uk/pdbsum/4quv PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4quv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4quv OCA], [https://pdbe.org/4quv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4quv RCSB], [https://www.ebi.ac.uk/pdbsum/4quv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4quv ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ERG_META2 ERG_META2] Reduces the C14=C15 double bond of 4,4-dimethyl-cholesta-8,14,24-trienol to produce 4,4-dimethyl-cholesta-8,24-dienol. Complements the deletion of the Delta(14)-sterol reductase gene ERG24 in yeast.<ref>PMID:25307054</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Blobel, G.]]
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[[Category: Large Structures]]
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[[Category: Li, X.]]
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[[Category: Methylotuvimicrobium alcaliphilum 20Z]]
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[[Category: Cholesterol biosynthesis]]
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[[Category: Blobel G]]
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[[Category: Membrane protein]]
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[[Category: Li X]]
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[[Category: Oxidoreductase]]
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Current revision

Structure of an integral membrane delta(14)-sterol reductase

PDB ID 4quv

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