4rbn
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The crystal structure of Nitrosomonas europaea sucrose synthase: Insights into the evolutionary origin of sucrose metabolism in prokaryotes== |
| - | + | <StructureSection load='4rbn' size='340' side='right'caption='[[4rbn]], [[Resolution|resolution]] 3.05Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4rbn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Nitrosomonas_europaea Nitrosomonas europaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RBN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RBN FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.05Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rbn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rbn OCA], [https://pdbe.org/4rbn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rbn RCSB], [https://www.ebi.ac.uk/pdbsum/4rbn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rbn ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SUS_NITEU SUS_NITEU] Catalyzes the reversible conversion of sucrose and a nucleotide disphosphate (NDP) into fructose and NDP-glucose; although the reaction is freely reversible in vitro, the physiological reaction seems to be sucrose cleavage. Unlike characterized plant enzymes prefers ADP as a cosubstrate, whereas plants prefer UDP (PubMed:25846332, PubMed:26013491). The KM for sucrose is 8-fold lower in the presence of ADP than UDP (PubMed:25846332). Its preference for ADP over UDP suggests it may directly link sucrose and glycogen metabolism (Probable).<ref>PMID:25846332</ref> <ref>PMID:26013491</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Nitrosomonas europaea]] | ||
| + | [[Category: Asencion Diez MD]] | ||
| + | [[Category: Ballicora MA]] | ||
| + | [[Category: Figueroa CM]] | ||
| + | [[Category: Iglesias AA]] | ||
| + | [[Category: Liu D]] | ||
| + | [[Category: Machtey M]] | ||
| + | [[Category: Wu R]] | ||
Current revision
The crystal structure of Nitrosomonas europaea sucrose synthase: Insights into the evolutionary origin of sucrose metabolism in prokaryotes
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