3tbi

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:48, 27 November 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal structure of T4 gp33 bound to E. coli RNAP beta-flap domain==
==Crystal structure of T4 gp33 bound to E. coli RNAP beta-flap domain==
-
<StructureSection load='3tbi' size='340' side='right' caption='[[3tbi]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
+
<StructureSection load='3tbi' size='340' side='right'caption='[[3tbi]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3tbi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4] and [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TBI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TBI FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3tbi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TBI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TBI FirstGlance]. <br>
-
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">33, gp33 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 Enterobacteria phage T4]), b3987, groN, JW3950, nitB, rif, ron, rpoB, stl, stv, tabD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tbi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tbi OCA], [https://pdbe.org/3tbi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tbi RCSB], [https://www.ebi.ac.uk/pdbsum/3tbi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tbi ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tbi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tbi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tbi RCSB], [http://www.ebi.ac.uk/pdbsum/3tbi PDBsum]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/RPOB_ECOLI RPOB_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01321]
+
[https://www.uniprot.org/uniprot/LTACT_BPT4 LTACT_BPT4] Activates transcription at late promoters when the sliding clamp is present (PubMed:33602900). Binds to both the host RNA polymerase (RNAP) and the upstream dsDNA (PubMed:33602900, PubMed:8106327).[HAMAP-Rule:MF_04165]<ref>PMID:33602900</ref> <ref>PMID:8106327</ref>
 +
 
 +
==See Also==
 +
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
 +
== References ==
 +
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: DNA-directed RNA polymerase]]
 
-
[[Category: Enterobacteria phage t4]]
 
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Campbell, E A]]
+
[[Category: Escherichia virus T4]]
-
[[Category: Darst, S A]]
+
[[Category: Large Structures]]
-
[[Category: Twist, K A.F]]
+
[[Category: Campbell EA]]
-
[[Category: Transcription]]
+
[[Category: Darst SA]]
-
[[Category: Transcription accessory protein]]
+
[[Category: Twist KAF]]

Current revision

Crystal structure of T4 gp33 bound to E. coli RNAP beta-flap domain

PDB ID 3tbi

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools