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3zmj

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==Structure of E.coli rhomboid protease GlpG in complex with monobactam L61==
==Structure of E.coli rhomboid protease GlpG in complex with monobactam L61==
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<StructureSection load='3zmj' size='340' side='right' caption='[[3zmj]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='3zmj' size='340' side='right'caption='[[3zmj]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3zmj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZMJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZMJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3zmj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZMJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZMJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BNG:B-NONYLGLUCOSIDE'>BNG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=L61:2-METHYLPROPYL+N-[(1R)-3-OXIDANYLIDENE-1-PHENYL-PROPYL]CARBAMATE'>L61</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zmh|3zmh]], [[3zmi|3zmi]], [[3zot|3zot]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BNG:B-NONYLGLUCOSIDE'>BNG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=L61:2-METHYLPROPYL+N-[(1R)-3-OXIDANYLIDENE-1-PHENYL-PROPYL]CARBAMATE'>L61</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Rhomboid_protease Rhomboid protease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.105 3.4.21.105] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zmj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zmj OCA], [https://pdbe.org/3zmj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zmj RCSB], [https://www.ebi.ac.uk/pdbsum/3zmj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zmj ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zmj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zmj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zmj RCSB], [http://www.ebi.ac.uk/pdbsum/3zmj PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GLPG_ECOLI GLPG_ECOLI]] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.<ref>PMID:17099694</ref> <ref>PMID:16216077</ref>
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[https://www.uniprot.org/uniprot/GLPG_ECOLI GLPG_ECOLI] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.<ref>PMID:17099694</ref> <ref>PMID:16216077</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3zmj" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Rhomboid protease]]
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[[Category: Large Structures]]
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[[Category: Freeman, M]]
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[[Category: Freeman M]]
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[[Category: Large, J M]]
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[[Category: Large JM]]
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[[Category: Pierrat, O]]
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[[Category: Pierrat O]]
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[[Category: Vinothkumar, K R]]
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[[Category: Vinothkumar KR]]
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[[Category: Acyl enzyme]]
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[[Category: Anitbiotic]]
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[[Category: Beta lactam]]
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[[Category: Hydrolase]]
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[[Category: Intra-membrane protease]]
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Current revision

Structure of E.coli rhomboid protease GlpG in complex with monobactam L61

PDB ID 3zmj

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