4per

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==Structure of Gallus gallus ribonuclease inhibitor complexed with Gallus gallus ribonuclease I==
==Structure of Gallus gallus ribonuclease inhibitor complexed with Gallus gallus ribonuclease I==
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<StructureSection load='4per' size='340' side='right' caption='[[4per]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
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<StructureSection load='4per' size='340' side='right'caption='[[4per]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4per]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PER OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PER FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4per]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PER OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PER FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4peq|4peq]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4per FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4per OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4per RCSB], [http://www.ebi.ac.uk/pdbsum/4per PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4per FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4per OCA], [https://pdbe.org/4per PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4per RCSB], [https://www.ebi.ac.uk/pdbsum/4per PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4per ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ANGI_CHICK ANGI_CHICK]] Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo (By similarity).
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[https://www.uniprot.org/uniprot/Q5ZIY8_CHICK Q5ZIY8_CHICK]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4per" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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*[[Ribonuclease inhibitor|Ribonuclease inhibitor]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bianchetti, C M]]
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[[Category: Gallus gallus]]
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[[Category: Fox, B G]]
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[[Category: Large Structures]]
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[[Category: Lomax, J E]]
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[[Category: Bianchetti CM]]
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[[Category: Raines, R T]]
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[[Category: Fox BG]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Lomax JE]]
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[[Category: Leucine-rich repeat]]
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[[Category: Raines RT]]
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[[Category: Protein-protein complex]]
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Current revision

Structure of Gallus gallus ribonuclease inhibitor complexed with Gallus gallus ribonuclease I

PDB ID 4per

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