Sandbox jmu01
From Proteopedia
(Difference between revisions)
(New page: ==Your Heading Here (maybe something like 'Structure')== <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> This is a default text for you...) |
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- | == | + | Ć==HIV Protease Inhibitor == |
- | <StructureSection load=' | + | <StructureSection load='3O99' size='340' side='right' caption='Caption for this structure' scene=''> |
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- | = | + | We can clean up the structure some by creating a view |
+ | <scene name='71/713483/Start/1'>without the solvent molecules</scene>. | ||
- | == Disease == | ||
- | + | This article describes the crystallization of HIV Protease with various inhibitors including the K13 inhibitor shown in this structure. <ref>http://dx.doi.org/10.1016/j.chembiol.2013.07.014</ref> | |
- | == | + | Here I have highlighted key nonpolar residues in the <scene name='71/713483/Active_site_zoom/1'>active site</scene> that make van der Waals interactions with K13. The inhibitor has a longer hydrophobic region so it binds tighter here. |
+ | Here is a space-filling representation with <scene name='71/713483/Active_site_surface_hydrophobi/1'>polar and nonpolar coloring .</scene> | ||
- | + | {{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}} | |
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> |
Current revision
Ć==HIV Protease Inhibitor ==
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