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Sandbox jmu01
From Proteopedia
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| - | ==HIV Protease Inhibitor | + | Ć==HIV Protease Inhibitor == |
<StructureSection load='3O99' size='340' side='right' caption='Caption for this structure' scene=''> | <StructureSection load='3O99' size='340' side='right' caption='Caption for this structure' scene=''> | ||
| - | This is a default text for your page '''Sandbox jmu01'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
| - | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
| - | = | + | We can clean up the structure some by creating a view |
| - | + | <scene name='71/713483/Start/1'>without the solvent molecules</scene>. | |
| - | <scene name='71/713483/Rainbow/1'>scene</scene> | ||
| - | {{STRUCTURE_3O99 | PDB=2DQX}} | ||
| + | This article describes the crystallization of HIV Protease with various inhibitors including the K13 inhibitor shown in this structure. <ref>http://dx.doi.org/10.1016/j.chembiol.2013.07.014</ref> | ||
| - | + | Here I have highlighted key nonpolar residues in the <scene name='71/713483/Active_site_zoom/1'>active site</scene> that make van der Waals interactions with K13. The inhibitor has a longer hydrophobic region so it binds tighter here. | |
| + | Here is a space-filling representation with <scene name='71/713483/Active_site_surface_hydrophobi/1'>polar and nonpolar coloring .</scene> | ||
| + | |||
| + | {{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}} | ||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Current revision
Ć==HIV Protease Inhibitor ==
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