4d7k
From Proteopedia
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==Crystal structure of N,N-8-amino-8-demethyl-D-riboflavin dimethyltransferase (RosA) from Streptomyces davawensis== | ==Crystal structure of N,N-8-amino-8-demethyl-D-riboflavin dimethyltransferase (RosA) from Streptomyces davawensis== | ||
| - | <StructureSection load='4d7k' size='340' side='right' caption='[[4d7k]], [[Resolution|resolution]] 2.22Å' scene=''> | + | <StructureSection load='4d7k' size='340' side='right'caption='[[4d7k]], [[Resolution|resolution]] 2.22Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4d7k]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D7K OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4d7k]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_davaonensis_JCM_4913 Streptomyces davaonensis JCM 4913]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D7K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D7K FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.22Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d7k OCA], [https://pdbe.org/4d7k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d7k RCSB], [https://www.ebi.ac.uk/pdbsum/4d7k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d7k ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ROSA_STRDJ ROSA_STRDJ] Catalyzes the S-adenosyl methionine-dependent conversion of 8-amino-8-demethyl-D-riboflavin (AF) into 8-methylamino-8-demethyl-D-riboflavin (MAF) and roseoflavin (RoF), the last two steps in the biosynthesis of the antibiotic roseoflavin.<ref>PMID:21911488</ref> <ref>PMID:26913589</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Streptomyces davaonensis JCM 4913]] |
| - | [[Category: | + | [[Category: Gruber K]] |
| - | [[Category: | + | [[Category: Uhl MK]] |
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Current revision
Crystal structure of N,N-8-amino-8-demethyl-D-riboflavin dimethyltransferase (RosA) from Streptomyces davawensis
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