User:Carlos Vázquez García/TFG/Parte7

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<p style="font-size:20px;border-bottom:1px solid #ac9de3;background-color:#eae8f5;padding:5px;">8. Bibliografía</p>
<p style="font-size:20px;border-bottom:1px solid #ac9de3;background-color:#eae8f5;padding:5px;">8. Bibliografía</p>
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[1] Y. Pylayeva-Gupta, E. Grabocka and D. Bar-Sagi (2011) Ras oncogenes: weaving a tumorigenic web. Nature Reviews Cancer 11, 761-774. PMID 21993244
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[1] Pylayeva-Gupta Y., Grabocka E. and Bar-Sagi D. (2011) Ras oncogenes: weaving a tumorigenic web. Nature Reviews Cancer 11, 761-774.
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[2] Kirsten WH, Schauf V, McCoy J (1970). "Properties of a murine sarcoma virus". Bibl Haematol (36): 246–9. PMID 553835
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[2] Fernández-Medarde, Santos E., (2011). Ras in Cancer and Developmental Diseases.Genes & Cancer. 2, 344–358.
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[3] Uniprot.org. (2016). KRAS - GTPase KRas precursor - Homo sapiens (Human) - KRAS gene & protein. [En línea] Disponible en: http://www.uniprot.org/uniprot/P01116 [Visitado 15 Mar. 2016].
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[3] Uniprot.org, (2016). KRAS - GTPase KRas precursor - Homo sapiens (Human) - KRAS gene & protein. [En línea] Disponible en: http://www.uniprot.org/uniprot/P01116 [Visitado 15 Mar. 2016].
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[4] Ebi.ac.uk. (2014). Protein Data Bank. [En línea] Disponible en: http://www.ebi.ac.uk/pdbe/entry/pdb/4Q03 [Visitado 15 Mar. 2016].
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[4] Sun Q, Phan J, Friberg AR, Camper DV, Olejniczak ET, Fesik SW. Second-site screening of K-Ras in the presence of covalently attached first-site ligands [En línea] Disponible en:http://www.ebi.ac.uk/pdbe/entry/pdb/4Q03 [Visitado 15 Mar. 2016].
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[5] "Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity."
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[5] Maurer T., Garrenton L.S., Oh A., Pitts K., Anderson D.J., Skelton N.J., Fauber B.P., Pan B., Malek S., Stokoe D., Ludlam M.J., Bowman K.K., Wu J., Giannetti A.M., Starovasnik M.A., Mellman I., Jackson P.K., Rudolph J., Wang W., Fang G., (2012). Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proceedings of the National Academy of Sciences U.S.A. 109:5299-5304.
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Maurer T., Garrenton L.S., Oh A., Pitts K., Anderson D.J., Skelton N.J., Fauber B.P., Pan B., Malek S., Stokoe D., Ludlam M.J., Bowman K.K., Wu J., Giannetti A.M., Starovasnik M.A., Mellman I., Jackson P.K., Rudolph J., Wang W., Fang G.
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Proc. Natl. Acad. Sci. U.S.A. 109:5299-5304(2012).
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[6] Sancho López, P. (2010). Actividad enzimática. 1st ed. [ebook] Alcalá de Henares: Pilar Sáncho López, p.5. Disponible en: http://www3.uah.es/bioquimica/Sancho/farmacia/temas/tema-7_catalisis-enzimatica.pdf [Visitado 16 Mar. 2016].
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[6] Sancho López, P., (2010). Actividad enzimática. [ebook] Alcalá de Henares: Pilar Sáncho López, p.5. Disponible en: http://www3.uah.es/bioquimica/Sancho/farmacia/temas/tema-7_catalisis-enzimatica.pdf [Visitado 16 Mar. 2016].
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[7] Maurer T, e. (2016). Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. - PubMed - NCBI. [En línea] Ncbi.nlm.nih.gov. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/22431598 [Visitado 16 Mar. 2016].
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[7] Bollag, G., Adler, F., elMasry, N., McCabe, P., Conner, E., Thompson, P., McCormick, F. and Shannon, K. (1996). Biochemical characterization of a novel KRAS insertion mutation from a human leukemia. journal of biological chemistry, 271, 32491-32494.
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[8] Bollag G1, Adler F, elMasry N, McCabe PC, Conner E Jr, Thompson P, McCormick F, Shannon K. (1996). "Biochemical characterization of a novel KRAS insertion mutation from a human leukemia." [En línea] Ncbi.nlm.nih.gov. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/8955068 [Visitado 16 Mar. 2016].
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[8] Fletcher. C., (2011). Panitumumab: The KRAS story. [En línea] Disponible en: http://www.ema.europa.eu/docs/en_GB/document_library/Presentation/2011/11/WC500118101.pdf [Visitado 16 Mar. 2016].
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[9] Fletcher, C. (2011). Panitumumab: The KRAS Story. [En línea] Disponible en: http://www.ema.europa.eu/docs/en_GB/document_library/Presentation/2011/11/WC500118101.pdf [Visitado 16 Mar. 2016].
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[9] V8rik, 17 January 2009. Basic amino acid condensation. [Imagen] Disponible en: https://commons.wikimedia.org/wiki/File:AminoacidCondensation.svg [Visitado 16 Mar. 2016].
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[10] Wikimedia Foundation, (n.d.). The condensation of two amino acids to form a peptide bond with expulsion of water.. [Imagen] Disponible en: https://en.wikipedia.org/wiki/Condensation_reaction [Visitado 16 Mar. 2016].
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[10] UniProt, (n.d.). K-RAS 2A Sequence. [Imagen] Disponible en: http://www.uniprot.org/uniprot/P01116 [Visitado 16 Mar. 2016].
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[11] UniProt, (n.d.). K-RAS 2A Sequence. [Imagen] Disponible en: http://www.uniprot.org/uniprot/P01116 [Visitado 16 Mar. 2016].
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[11] Uniprot.org, (2016). KRAS - GTPase KRas precursor - Homo sapiens (Human) - KRAS gene & protein. [En línea] Disponible en: http://www.uniprot.org/uniprot/P01116 [Visitado 16 Mar. 2016].
-
[12] Uniprot.org. (2016). KRAS - GTPase KRas precursor - Homo sapiens (Human) - KRAS gene & protein. [En línea] Disponible en: http://www.uniprot.org/uniprot/P01116 [Visitado 16 Mar. 2016].
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[12] Tong Y, Tempel W, Shen L, Arrowsmith CH, Edwards AM, Sundstrom M, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC), (2009). Human K-Ras (Q61H) in complex with a GTP analogue. [Imagen] Disponible en: http://www.ebi.ac.uk/pdbe/entry/pdb/3gft/bound/GNP [Visitado 16 Mar. 2016].
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[13] Protein Data Bank, (n.d.). Interacciones entre GNP y el bolsillo de K-RAS. [Imagen] Disponible en: http://www.ebi.ac.uk/pdbe/entry/pdb/3gft/bound/GNP [Visitado 16 Mar. 2016].
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[13] Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M., (2013). Crystal structure of small molecule vinylsulfonamide 7 covalently bound to K-Ras G12C. [Imagen] Disponible en: http://www.ebi.ac.uk/pdbe/entry/pdb/4m1o/bound/GDP [Visitado 16 Mar. 2016]
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[14] Protein Data Bank, (n.d.). Interacciones entre GDP y el bolsillo de K-RAS. [Imagen] Disponible en:http://www.ebi.ac.uk/pdbe/entry/pdb/4m1o/bound/GDP [Visitado 16 Mar. 2016]
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[14] Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M., (2013). Crystal structure of small molecule vinylsulfonamide 7 covalently bound to K-Ras G12C. [Imagen] Disponible en: http://www.rcsb.org/pdb/explore/explore.do?pdbId=4M1O [Visitado 16 Mar. 2016].
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[15] Protein Data Bank, (n.d). Interacción esquematizada del GDP con el bolsillo de K-RAS. [Imagen] Disponible en: http://www.rcsb.org/pdb/explore/explore.do?pdbId=4M1O [Visitado 16 Mar. 2016].
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[15] Sun, Q., Phan, J., Friberg, A., Camper, D.V., Olejniczak, E.T., Fesik, S.W., (2014). Second-site screening of K-Ras in the presence of covalently attached first-site ligands. [Imagen] Disponible en: http://www.ebi.ac.uk/pdbe/entry/pdb/4q03/bound/MG [Visitado 16 Mar. 2016].
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[16] Protein Data Bank, (n.d). Interacciones del catión Mg2+ con el bolsillo de K-RAS.. [Imagen] Disponible en: http://www.ebi.ac.uk/pdbe/entry/pdb/4q03/bound/MG [Visitado 16 Mar. 2016].
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[16] Sun, Q., Phan, J., Friberg, A., Camper, D.V., Olejniczak, E.T., Fesik, S.W., (2014). Second-site screening of K-Ras in the presence of covalently attached first-site ligands. [Imagen] Disponible en: http://www.rcsb.org/pdb/explore/explore.do?pdbId=4Q03 [Visitado 16 Mar. 2016].
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[17] Protein Data Bank, (n.d.). [Imagen] Disponible en: http://www.rcsb.org/pdb/explore/explore.do?pdbId=4Q03 [Visitado 16 Mar. 2016].
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[17] Oh, A., Maurer, T., Garrenton, L.S., Pitts, K., Anderson, D.J., Skelton, N.J., Fauber, B.P., Pan, B., Malek, S., Stokoe, D., Ludlam, M., Bowman, K.K., Wu, J., Giannetti, A.M., Starovasnik, M.A., Mellman, I., Jackson, P.K., Ruldolph, J., Fang, G., Wang, W. (2012). Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. [Imagen] Disponible en: http://www.rcsb.org/pdb/explore/explore.do?pdbId=4DSO [Visitado 16 Mar. 2016].
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[18] Protein Data Bank, (n.d.). [Imagen] Disponible en: http://www.rcsb.org/pdb/explore/explore.do?pdbId=4DSO [Visitado 16 Mar. 2016].
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[18] Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M., (2013). Crystal structure of small molecule vinylsulfonamide 7 covalently bound to K-Ras G12C. [Imagen] Disponible en: http://www.rcsb.org/pdb/explore/explore.do?pdbId=4M1O [Visitado 16 Mar. 2016].
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[19] Protein Data Bank, (n.d.). [Imagen] Disponible en: http://www.rcsb.org/pdb/explore/explore.do?pdbId=4M1O [Visitado 16 Mar. 2016].
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Current revision

8. Bibliografía

[1] Pylayeva-Gupta Y., Grabocka E. and Bar-Sagi D. (2011) Ras oncogenes: weaving a tumorigenic web. Nature Reviews Cancer 11, 761-774.

[2] Fernández-Medarde, Santos E., (2011). Ras in Cancer and Developmental Diseases.Genes & Cancer. 2, 344–358.

[3] Uniprot.org, (2016). KRAS - GTPase KRas precursor - Homo sapiens (Human) - KRAS gene & protein. [En línea] Disponible en: http://www.uniprot.org/uniprot/P01116 [Visitado 15 Mar. 2016].

[4] Sun Q, Phan J, Friberg AR, Camper DV, Olejniczak ET, Fesik SW. Second-site screening of K-Ras in the presence of covalently attached first-site ligands [En línea] Disponible en:http://www.ebi.ac.uk/pdbe/entry/pdb/4Q03 [Visitado 15 Mar. 2016].

[5] Maurer T., Garrenton L.S., Oh A., Pitts K., Anderson D.J., Skelton N.J., Fauber B.P., Pan B., Malek S., Stokoe D., Ludlam M.J., Bowman K.K., Wu J., Giannetti A.M., Starovasnik M.A., Mellman I., Jackson P.K., Rudolph J., Wang W., Fang G., (2012). Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proceedings of the National Academy of Sciences U.S.A. 109:5299-5304.

[6] Sancho López, P., (2010). Actividad enzimática. [ebook] Alcalá de Henares: Pilar Sáncho López, p.5. Disponible en: http://www3.uah.es/bioquimica/Sancho/farmacia/temas/tema-7_catalisis-enzimatica.pdf [Visitado 16 Mar. 2016].

[7] Bollag, G., Adler, F., elMasry, N., McCabe, P., Conner, E., Thompson, P., McCormick, F. and Shannon, K. (1996). Biochemical characterization of a novel KRAS insertion mutation from a human leukemia. journal of biological chemistry, 271, 32491-32494.

[8] Fletcher. C., (2011). Panitumumab: The KRAS story. [En línea] Disponible en: http://www.ema.europa.eu/docs/en_GB/document_library/Presentation/2011/11/WC500118101.pdf [Visitado 16 Mar. 2016].

[9] V8rik, 17 January 2009. Basic amino acid condensation. [Imagen] Disponible en: https://commons.wikimedia.org/wiki/File:AminoacidCondensation.svg [Visitado 16 Mar. 2016].

[10] UniProt, (n.d.). K-RAS 2A Sequence. [Imagen] Disponible en: http://www.uniprot.org/uniprot/P01116 [Visitado 16 Mar. 2016].

[11] Uniprot.org, (2016). KRAS - GTPase KRas precursor - Homo sapiens (Human) - KRAS gene & protein. [En línea] Disponible en: http://www.uniprot.org/uniprot/P01116 [Visitado 16 Mar. 2016].

[12] Tong Y, Tempel W, Shen L, Arrowsmith CH, Edwards AM, Sundstrom M, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC), (2009). Human K-Ras (Q61H) in complex with a GTP analogue. [Imagen] Disponible en: http://www.ebi.ac.uk/pdbe/entry/pdb/3gft/bound/GNP [Visitado 16 Mar. 2016].

[13] Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M., (2013). Crystal structure of small molecule vinylsulfonamide 7 covalently bound to K-Ras G12C. [Imagen] Disponible en: http://www.ebi.ac.uk/pdbe/entry/pdb/4m1o/bound/GDP [Visitado 16 Mar. 2016]

[14] Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M., (2013). Crystal structure of small molecule vinylsulfonamide 7 covalently bound to K-Ras G12C. [Imagen] Disponible en: http://www.rcsb.org/pdb/explore/explore.do?pdbId=4M1O [Visitado 16 Mar. 2016].

[15] Sun, Q., Phan, J., Friberg, A., Camper, D.V., Olejniczak, E.T., Fesik, S.W., (2014). Second-site screening of K-Ras in the presence of covalently attached first-site ligands. [Imagen] Disponible en: http://www.ebi.ac.uk/pdbe/entry/pdb/4q03/bound/MG [Visitado 16 Mar. 2016].

[16] Sun, Q., Phan, J., Friberg, A., Camper, D.V., Olejniczak, E.T., Fesik, S.W., (2014). Second-site screening of K-Ras in the presence of covalently attached first-site ligands. [Imagen] Disponible en: http://www.rcsb.org/pdb/explore/explore.do?pdbId=4Q03 [Visitado 16 Mar. 2016].

[17] Oh, A., Maurer, T., Garrenton, L.S., Pitts, K., Anderson, D.J., Skelton, N.J., Fauber, B.P., Pan, B., Malek, S., Stokoe, D., Ludlam, M., Bowman, K.K., Wu, J., Giannetti, A.M., Starovasnik, M.A., Mellman, I., Jackson, P.K., Ruldolph, J., Fang, G., Wang, W. (2012). Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. [Imagen] Disponible en: http://www.rcsb.org/pdb/explore/explore.do?pdbId=4DSO [Visitado 16 Mar. 2016].

[18] Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M., (2013). Crystal structure of small molecule vinylsulfonamide 7 covalently bound to K-Ras G12C. [Imagen] Disponible en: http://www.rcsb.org/pdb/explore/explore.do?pdbId=4M1O [Visitado 16 Mar. 2016].

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