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5ug4
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of spermidine N-acetyltransferase SpeG from Vibrio cholerae== | |
| + | <StructureSection load='5ug4' size='340' side='right'caption='[[5ug4]], [[Resolution|resolution]] 2.15Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5ug4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae_O1 Vibrio cholerae O1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UG4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UG4 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=MOH:METHANOL'>MOH</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ug4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ug4 OCA], [https://pdbe.org/5ug4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ug4 RCSB], [https://www.ebi.ac.uk/pdbsum/5ug4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ug4 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ATDA_VIBCH ATDA_VIBCH] Involved in the protection against polyamine toxicity by regulating their concentration. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to the primary amino groups of spermidine to yield N(1)- and N(8)-acetylspermidine. It can use polyamines such as spermine and N(1)-acetylspermine, but not putrescine or cadaverine.<ref>PMID:23184347</ref> <ref>PMID:25623305</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Spermidine/spermine N-acetyltransferase|Spermidine/spermine N-acetyltransferase]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Filippova | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Vibrio cholerae O1]] |
| - | [[Category: | + | [[Category: Anderson WF]] |
| - | [[Category: Shuvalova | + | [[Category: Filippova EV]] |
| + | [[Category: Kiryukhina O]] | ||
| + | [[Category: Minasov G]] | ||
| + | [[Category: Shuvalova L]] | ||
Current revision
Structure of spermidine N-acetyltransferase SpeG from Vibrio cholerae
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