5vy3

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(New page: ==Thermoplasma acidophilum 20S Proteasome using 200keV with stage position== <StructureSection load='5vy3' size='340' side='right' caption='5vy3, resolution 3.10&Aring;...)
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==Thermoplasma acidophilum 20S Proteasome using 200keV with stage position==
==Thermoplasma acidophilum 20S Proteasome using 200keV with stage position==
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<StructureSection load='5vy3' size='340' side='right' caption='[[5vy3]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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<SX load='5vy3' size='340' side='right' viewer='molstar' caption='[[5vy3]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5vy3]] is a 28 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VY3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VY3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5vy3]] is a 28 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VY3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VY3 FirstGlance]. <br>
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Proteasome_endopeptidase_complex Proteasome endopeptidase complex], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.25.1 3.4.25.1] </span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vy3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vy3 OCA], [http://pdbe.org/5vy3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vy3 RCSB], [http://www.ebi.ac.uk/pdbsum/5vy3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vy3 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vy3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vy3 OCA], [https://pdbe.org/5vy3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vy3 RCSB], [https://www.ebi.ac.uk/pdbsum/5vy3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vy3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PSA_THEAC PSA_THEAC]] Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The T.acidophilum proteasome is able to cleave oligopeptides after Tyr, Leu, Phe, and to a lesser extent after Glu and Arg. Thus, displays chymotrypsin-like activity and low level of caspase-like and trypsin-like activities.<ref>PMID:8999862</ref> [[http://www.uniprot.org/uniprot/PSB_THEAC PSB_THEAC]] Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The T.acidophilum proteasome is able to cleave oligopeptides after Tyr, Leu, Phe, and to a lesser extent after Glu and Arg. Thus, displays chymotrypsin-like activity and low level of caspase-like and trypsin-like activities.<ref>PMID:8999862</ref>
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[https://www.uniprot.org/uniprot/PSA_THEAC PSA_THEAC] Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The T.acidophilum proteasome is able to cleave oligopeptides after Tyr, Leu, Phe, and to a lesser extent after Glu and Arg. Thus, displays chymotrypsin-like activity and low level of caspase-like and trypsin-like activities.<ref>PMID:8999862</ref>
==See Also==
==See Also==
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*[[Proteasome|Proteasome]]
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*[[Proteasome 3D structures|Proteasome 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
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</StructureSection>
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</SX>
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[[Category: Proteasome endopeptidase complex]]
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[[Category: Large Structures]]
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[[Category: Herzik, M A]]
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[[Category: Thermoplasma acidophilum]]
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[[Category: Lander, G C]]
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[[Category: Herzik Jr MA]]
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[[Category: Wu, M]]
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[[Category: Lander GC]]
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[[Category: Hydrolase]]
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[[Category: Wu M]]
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[[Category: Proteasome]]
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Current revision

Thermoplasma acidophilum 20S Proteasome using 200keV with stage position

5vy3, resolution 3.10Å

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