2nrf

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==Crystal Structure of GlpG, a Rhomboid family intramembrane protease==
==Crystal Structure of GlpG, a Rhomboid family intramembrane protease==
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<StructureSection load='2nrf' size='340' side='right' caption='[[2nrf]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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<StructureSection load='2nrf' size='340' side='right'caption='[[2nrf]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2nrf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. The August 2011 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Rhomboid Protease GlpG'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2011_8 10.2210/rcsb_pdb/mom_2011_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NRF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NRF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2nrf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. The August 2011 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Rhomboid Protease GlpG'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2011_8 10.2210/rcsb_pdb/mom_2011_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NRF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NRF FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">glpG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2nrf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nrf OCA], [http://pdbe.org/2nrf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2nrf RCSB], [http://www.ebi.ac.uk/pdbsum/2nrf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2nrf ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nrf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nrf OCA], [https://pdbe.org/2nrf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nrf RCSB], [https://www.ebi.ac.uk/pdbsum/2nrf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nrf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GLPG_ECOLI GLPG_ECOLI]] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.<ref>PMID:17099694</ref> <ref>PMID:16216077</ref>
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[https://www.uniprot.org/uniprot/GLPG_ECOLI GLPG_ECOLI] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.<ref>PMID:17099694</ref> <ref>PMID:16216077</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nr/2nrf_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nr/2nrf_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 2nrf" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2nrf" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Rhomboid protease|Rhomboid protease]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Rhomboid Protease GlpG]]
[[Category: Rhomboid Protease GlpG]]
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[[Category: Feng, L]]
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[[Category: Feng L]]
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[[Category: Gu, L]]
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[[Category: Gu L]]
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[[Category: Shi, Y]]
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[[Category: Shi Y]]
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[[Category: Wu, Z]]
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[[Category: Wu Z]]
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[[Category: Yan, H]]
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[[Category: Yan H]]
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[[Category: Yan, N]]
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[[Category: Yan N]]
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[[Category: Integral membrane protein]]
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[[Category: Membrane protein]]
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Current revision

Crystal Structure of GlpG, a Rhomboid family intramembrane protease

PDB ID 2nrf

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