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5x5i

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==The X-ray crystal structure of a TetR family transcription regulator RcdA involved in the regulation of biofilm formation in Escherichia coli==
==The X-ray crystal structure of a TetR family transcription regulator RcdA involved in the regulation of biofilm formation in Escherichia coli==
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<StructureSection load='5x5i' size='340' side='right' caption='[[5x5i]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
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<StructureSection load='5x5i' size='340' side='right'caption='[[5x5i]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5x5i]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X5I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5X5I FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5x5i]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X5I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5X5I FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.554&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5x5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x5i OCA], [http://pdbe.org/5x5i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5x5i RCSB], [http://www.ebi.ac.uk/pdbsum/5x5i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5x5i ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5x5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x5i OCA], [https://pdbe.org/5x5i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5x5i RCSB], [https://www.ebi.ac.uk/pdbsum/5x5i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5x5i ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RCDA_ECOLI RCDA_ECOLI]] Regulates the expression of a number of genes involved in biofilm formation and stress response. Target genes include six stress-response transcriptional regulators: csgD, which is a master regulator of biofilm formation, appY, sxy, ycgF, fimB and rcdA itself. This indicates that a large number of genes must be regulated indirectly via these transcriptional regulators. Acts by binding to the upstream region of its target genes.<ref>PMID:23233451</ref>
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[https://www.uniprot.org/uniprot/RCDA_ECOLI RCDA_ECOLI] Regulates the expression of a number of genes involved in biofilm formation and stress response. Target genes include six stress-response transcriptional regulators: csgD, which is a master regulator of biofilm formation, appY, sxy, ycgF, fimB and rcdA itself. This indicates that a large number of genes must be regulated indirectly via these transcriptional regulators. Acts by binding to the upstream region of its target genes.<ref>PMID:23233451</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5x5i" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5x5i" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[RcdA|RcdA]]
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*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Hirata, A]]
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[[Category: Escherichia coli K-12]]
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[[Category: Ishihama, A]]
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[[Category: Large Structures]]
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[[Category: Nakano, M]]
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[[Category: Hirata A]]
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[[Category: Ogasawara, H]]
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[[Category: Ishihama A]]
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[[Category: Shimada, T]]
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[[Category: Nakano M]]
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[[Category: Sugino, H]]
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[[Category: Ogasawara H]]
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[[Category: Usui, M]]
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[[Category: Shimada T]]
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[[Category: Biofilm formation]]
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[[Category: Sugino H]]
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[[Category: Dimer]]
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[[Category: Usui M]]
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[[Category: Master transcription regulator]]
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[[Category: Tetr family transcription regulator]]
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[[Category: Transcription]]
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The X-ray crystal structure of a TetR family transcription regulator RcdA involved in the regulation of biofilm formation in Escherichia coli

PDB ID 5x5i

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