6fvb
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6fvb is ON HOLD Authors: Vera Rodriguez, A., Huyton, T., Gorlich, D. Description: Structure of Lph2 , a novel bidirectional nuclear transport recep...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Lph2 , a novel bidirectional nuclear transport receptor in S. cerevisiae== | |
| - | + | <StructureSection load='6fvb' size='340' side='right'caption='[[6fvb]], [[Resolution|resolution]] 3.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6fvb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FVB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6FVB FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.297Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | [[Category: Gorlich | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6fvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fvb OCA], [https://pdbe.org/6fvb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6fvb RCSB], [https://www.ebi.ac.uk/pdbsum/6fvb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6fvb ProSAT]</span></td></tr> |
| - | [[Category: Huyton | + | </table> |
| - | [[Category: Vera Rodriguez | + | == Function == |
| + | [https://www.uniprot.org/uniprot/KA120_YEAST KA120_YEAST] Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, RAN-dependent mechanism. Required for nuclear import of Ho endonuclease and RFP1, and involved in rRNA-processing and assembly or export of 60S ribosomal subunits.<ref>PMID:11071906</ref> <ref>PMID:12829295</ref> <ref>PMID:16507575</ref> <ref>PMID:16581791</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Gorlich D]] | ||
| + | [[Category: Huyton T]] | ||
| + | [[Category: Vera Rodriguez A]] | ||
Current revision
Structure of Lph2 , a novel bidirectional nuclear transport receptor in S. cerevisiae
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