6cjn

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'''Unreleased structure'''
 
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The entry 6cjn is ON HOLD until Paper Publication
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==Crystal Structure of Chalcone Isomerase from Medicago Sativa with the G95T mutation==
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<StructureSection load='6cjn' size='340' side='right'caption='[[6cjn]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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Authors: Burke, J.R., La Clair, J.J., Philippe, R.N., Pabis, A., Jez, J.M., Cortina, G., Kaltenbach, M., Bowman, M.E., Woods, K.B., Nelson, A.T., Tawfik, D.S., Kamerlin, S.C.L., Noel, J.P.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6cjn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Medicago_sativa Medicago sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CJN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CJN FirstGlance]. <br>
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Description: Crystal Structure of Chalcone Isomerase from Medicago Truncatula Complexed with 4,2',4',6'-Tetrahydroxychalcone
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Pabis, A]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cjn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cjn OCA], [https://pdbe.org/6cjn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cjn RCSB], [https://www.ebi.ac.uk/pdbsum/6cjn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cjn ProSAT]</span></td></tr>
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[[Category: Bowman, M.E]]
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</table>
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[[Category: Burke, J.R]]
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== Function ==
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[[Category: Tawfik, D.S]]
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[https://www.uniprot.org/uniprot/CFI1_MEDSA CFI1_MEDSA] Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin.<ref>PMID:10966651</ref> <ref>PMID:11955065</ref> <ref>PMID:11698411</ref>
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[[Category: Kaltenbach, M]]
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== References ==
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[[Category: La Clair, J.J]]
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<references/>
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[[Category: Noel, J.P]]
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__TOC__
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[[Category: Kamerlin, S.C.L]]
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</StructureSection>
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[[Category: Cortina, G]]
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[[Category: Large Structures]]
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[[Category: Nelson, A.T]]
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[[Category: Medicago sativa]]
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[[Category: Philippe, R.N]]
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[[Category: Bowman ME]]
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[[Category: Jez, J.M]]
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[[Category: Burke JR]]
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[[Category: Woods, K.B]]
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[[Category: Cortina G]]
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[[Category: Jez JM]]
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[[Category: Kaltenbach M]]
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[[Category: Kamerlin SCL]]
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[[Category: La Clair JJ]]
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[[Category: Nelson AT]]
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[[Category: Noel JP]]
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[[Category: Pabis A]]
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[[Category: Philippe RN]]
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[[Category: Tawfik DS]]
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[[Category: Woods KB]]

Current revision

Crystal Structure of Chalcone Isomerase from Medicago Sativa with the G95T mutation

PDB ID 6cjn

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