6j0z
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of AlpK== | |
| + | <StructureSection load='6j0z' size='340' side='right'caption='[[6j0z]], [[Resolution|resolution]] 2.89Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6j0z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_ambofaciens Streptomyces ambofaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J0Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6J0Z FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.889Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6j0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j0z OCA], [https://pdbe.org/6j0z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6j0z RCSB], [https://www.ebi.ac.uk/pdbsum/6j0z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6j0z ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q6VMI4_STRAM Q6VMI4_STRAM] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | AlpK is an essential monooxygenase involved in the biosynthesis of kinamycin. It catalyzes the C5-hyfroxylattion of the crucial benzo[b]-fluorence intermediate in kinamycin synthesis. However, the structure and mechanism of AlpK is unclear. Here, we report the first structure of AlpK in complex with FAD. Our structure sheds light on the catalytic mechanism of AlpK. | ||
| - | + | Crystal structure of AlpK: An essential monooxygenase involved in the biosynthesis of kinamycin.,Wang W, Li J, Li H, Fan K, Liu Y Biochem Biophys Res Commun. 2019 Mar 19;510(4):601-605. doi:, 10.1016/j.bbrc.2019.01.077. Epub 2019 Feb 7. PMID:30739782<ref>PMID:30739782</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 6j0z" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Streptomyces ambofaciens]] | ||
| + | [[Category: Liang H]] | ||
| + | [[Category: Liu Y]] | ||
| + | [[Category: Wang W]] | ||
Current revision
Crystal structure of AlpK
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