Sandbox S1
From Proteopedia
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' scene='80/807421/Tacrine/1'> | ' scene='80/807421/Tacrine/1'> | ||
- | + | [[1acj]] shows the crystal structure<ref>personal communication</ref> of Torpedo californica acetylcholinesterase (TcAChE) complexed with tacrine. | |
Tacrine is a '''reversible inhibitor''' of cholinesterase<ref>pmid 1122334</ref>. It was the first FDA approved drug for the treatment of Alzheimer's disease. | Tacrine is a '''reversible inhibitor''' of cholinesterase<ref>pmid 1122334</ref>. It was the first FDA approved drug for the treatment of Alzheimer's disease. | ||
- | Tacrine’s ring is stacked between the <scene name='80/807421/Tacrine/1'>aromatic rings</scene> of tryptophan 84 and phenylalanine 330 (W84 and F330). | + | Tacrine’s ring is stacked between the <scene name='80/807421/Tacrine/1'>aromatic rings</scene> of tryptophan 84 and phenylalanine 330 (W84 and F330). [http://cnn.com CNN ] |
== Function == | == Function == |
Current revision
Your Heading Here (maybe something like 'Structure')
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