This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Rhomboid protease
From Proteopedia
(Difference between revisions)
| (5 intermediate revisions not shown.) | |||
| Line 12: | Line 12: | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | *Rhomboid protease | + | *Rhomboid protease GlpG |
**[[2ic8]], [[2irv]], [[2nrf]], [[2o7l]], [[3b45]], [[2xov]], [[4njn]], [[4njp]] – EcGlpG core region – ''Escherichia coli '' <BR /> | **[[2ic8]], [[2irv]], [[2nrf]], [[2o7l]], [[3b45]], [[2xov]], [[4njn]], [[4njp]] – EcGlpG core region – ''Escherichia coli '' <BR /> | ||
| Line 22: | Line 22: | ||
**[[2gqc]] – RP N terminal – NMR – ''Pseudomonas aeruginosa''<br /> | **[[2gqc]] – RP N terminal – NMR – ''Pseudomonas aeruginosa''<br /> | ||
| - | *Rhomboid protease complex with inhibitor | + | *Rhomboid protease GlpG complex with inhibitor |
**[[2xow]], [[3zeb]] – EcGlpG core region + isocoumarin inhibitor <BR /> | **[[2xow]], [[3zeb]] – EcGlpG core region + isocoumarin inhibitor <BR /> | ||
| Line 28: | Line 28: | ||
**[[3ubb]] – EcGlpG core region + phosphonofluoridate inhibitor <BR /> | **[[3ubb]] – EcGlpG core region + phosphonofluoridate inhibitor <BR /> | ||
**[[3zmh]], [[3zmi]], [[3zmj]], [[3zot]] – EcGlpG core region + β-lactam inhibitor <BR /> | **[[3zmh]], [[3zmi]], [[3zmj]], [[3zot]] – EcGlpG core region + β-lactam inhibitor <BR /> | ||
| - | **[[5f5j]], [[5f5k]] – EcGlpG core region (mutant) + aldehyde inhibitor <BR /> | + | **[[6pj5]], [[6pj7]], [[6pj8]], [[6pj9]], [[6pja]], [[6pjp]], [[6pjq]], [[6pjr]], [[6pju]] – EcGlpG core region + peptide aldehyde inhibitor <BR /> |
| - | **[[4qo0]], [[4qo2]], [[5f5g]], [[5f5b]], [[5mtf]], [[5mt6]], [[5mt7]], [[5mt8]] – EcGlpG core region + peptide inhibitor <BR /> | + | **[[5f5j]], [[5f5k]], [[6pj4]] – EcGlpG core region (mutant) + peptide aldehyde inhibitor <BR /> |
| + | **[[4qo0]], [[4qo2]], [[5f5g]], [[5f5b]], [[5mtf]], [[5mt6]], [[5mt7]], [[5mt8]], [[6vj8]], [[6jv9]], [[6vjp]], [[6xro]], [[6xrp]] – EcGlpG core region + peptide inhibitor <BR /> | ||
**[[4qnz]] – EcGlpG core region (mutant) + peptide inhibitor <BR /> | **[[4qnz]] – EcGlpG core region (mutant) + peptide inhibitor <BR /> | ||
| + | |||
| + | *Rhomboid protease YqgP | ||
| + | |||
| + | **[[6r0j]] – YqpG – ''Bacillus subtilis'' - NMR <BR /> | ||
| + | |||
| + | *Rhomboid protease GluP | ||
| + | |||
| + | **[[7tj4]] – GluP + LytH – ''Staphylococcus aureus'' <BR /> | ||
}} | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
| |||||||||||
3D Structures of rhomboid protease
Updated on 17-October-2023
References
- ↑ Freeman M. Rhomboid proteases and their biological functions. Annu Rev Genet. 2008;42:191-210. doi: 10.1146/annurev.genet.42.110807.091628. PMID:18605900 doi:http://dx.doi.org/10.1146/annurev.genet.42.110807.091628
- ↑ Vinothkumar KR, Strisovsky K, Andreeva A, Christova Y, Verhelst S, Freeman M. The structural basis for catalysis and substrate specificity of a rhomboid protease. EMBO J. 2010 Oct 1. PMID:20890268 doi:10.1038/emboj.2010.243
