Raptor

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'''Raptor''' (Rap) or '''R'''egulatory-'''A'''ssociated '''P'''rotein of '''TOR''' 1 binds mTOR which controls cell growth, p70 S6 kinase α (S6K1) and the the initiation factor 4E binding protein 1 (4EBP1). The binding of Rap to mTOR is necessary for the mTOR-catayzed phosphorylation of the initiation factor binding protein
'''Raptor''' (Rap) or '''R'''egulatory-'''A'''ssociated '''P'''rotein of '''TOR''' 1 binds mTOR which controls cell growth, p70 S6 kinase α (S6K1) and the the initiation factor 4E binding protein 1 (4EBP1). The binding of Rap to mTOR is necessary for the mTOR-catayzed phosphorylation of the initiation factor binding protein
<ref>PMID:22732551</ref>.
<ref>PMID:22732551</ref>.
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</StructureSection>
 
==3D structures of raptor==
==3D structures of raptor==
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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[[Raptor 3D structures]]
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[[6bcu]] - hRap + mTOR + target of rapamycin complex + Rheb + 4EBP1 peptide - human - Cryo EM<br />
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[[5h64]] - hRap + mTOR + target of rapamycin complex - Cryo EM<br />
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[[6bcx]] - hRap + mTOR + target of rapamycin complex + 4EBP1 peptide - Cryo EM<br />
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[[5flc]] - hRap + mTOR + target of rapamycin complex + FKBP - Cryo EM<br />
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[[6sb2]] - hRap + mTOR + target of rapamycin complex + ras-related GTP-binding protein A,C - Cryo EM<br />
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[[6sb0]] - hRap + mTOR + target of rapamycin complex + ras-related GTP-binding protein A,C + proline-rich AKT1 substate - Cryo EM<br />
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[[6sb0]] - hRap + mTOR + ras-related GTP-binding protein A,C + regulator complex - Cryo EM<br />
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[[5ef5]] - Rap - ''Chaetomium thermophilum''<br />
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[[5wbi]] - AtRap - ''Arabidopsis thaliana''<br />
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[[5wbj]] - AtRap + 4EBP1 peptide<br />
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[[5wbk]] - AtRap + S6K1 peptide<br />
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[[5wbl]] - AtRap + PRAS40 peptide<br />
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[[5fjl]], [[5fld]] - Rap fiber head domain - Siadenovirus A<br />
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== References ==
== References ==
<references/>
<references/>
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</StructureSection>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Raptor (grey) in complex with human 4EBP1 peptide (mustard) PDB code 5wbj

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Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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