6ky0

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'''Unreleased structure'''
 
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The entry 6ky0 is ON HOLD until Paper Publication
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==Crystal structural of active-site human glutathione-specific gamma-glutamylcyclotransferase 2(ChaC2) mutant with Glutamate 74 replaced by Glutamine==
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<StructureSection load='6ky0' size='340' side='right'caption='[[6ky0]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
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Authors: Nguyen, T.K.Y., Han, B.W.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6ky0]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KY0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KY0 FirstGlance]. <br>
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Description: Crystal structural of active-site human glutathione-specific gamma-glutamylcyclotransferase 2(ChaC2) mutant with Glutamate 74 replaced by Glutamine
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.06&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ky0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ky0 OCA], [https://pdbe.org/6ky0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ky0 RCSB], [https://www.ebi.ac.uk/pdbsum/6ky0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ky0 ProSAT]</span></td></tr>
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[[Category: Han, B.W]]
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</table>
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[[Category: Nguyen, T.K.Y]]
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== Function ==
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[https://www.uniprot.org/uniprot/CHAC2_HUMAN CHAC2_HUMAN] Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.<ref>PMID:27913623</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Han BW]]
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[[Category: Nguyen TKY]]

Current revision

Crystal structural of active-site human glutathione-specific gamma-glutamylcyclotransferase 2(ChaC2) mutant with Glutamate 74 replaced by Glutamine

PDB ID 6ky0

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