1wlg
From Proteopedia
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<StructureSection load='1wlg' size='340' side='right'caption='[[1wlg]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='1wlg' size='340' side='right'caption='[[1wlg]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1wlg]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WLG OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[1wlg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WLG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WLG FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wlg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wlg OCA], [https://pdbe.org/1wlg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wlg RCSB], [https://www.ebi.ac.uk/pdbsum/1wlg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wlg ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FLGE_SALTY FLGE_SALTY] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wlg ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wlg ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | The bacterial flagellum is a motile organelle, and the flagellar hook is a short, highly curved tubular structure that connects the flagellar motor to the long filament acting as a helical propeller. The hook is made of about 120 copies of a single protein, FlgE, and its function as a nano-sized universal joint is essential for dynamic and efficient bacterial motility and taxis. It transmits the motor torque to the helical propeller over a wide range of its orientation for swimming and tumbling. Here we report a partial atomic model of the hook obtained by X-ray crystallography of FlgE31, a major proteolytic fragment of FlgE lacking unfolded terminal regions, and by electron cryomicroscopy and three-dimensional helical image reconstruction of the hook. The model reveals the intricate molecular interactions and a plausible switching mechanism for the hook to be flexible in bending but rigid against twisting for its universal joint function. | ||
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| - | Structure of the bacterial flagellar hook and implication for the molecular universal joint mechanism.,Samatey FA, Matsunami H, Imada K, Nagashima S, Shaikh TR, Thomas DR, Chen JZ, Derosier DJ, Kitao A, Namba K Nature. 2004 Oct 28;431(7012):1062-8. PMID:15510139<ref>PMID:15510139</ref> | ||
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 1wlg" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Fadel A. Samatey Group|Fadel A. Samatey Group]] | ||
| - | *[[Fadel A. Samatey Group (Japanese)|Fadel A. Samatey Group (Japanese)]] | ||
*[[Flagellar protein 3D structures|Flagellar protein 3D structures]] | *[[Flagellar protein 3D structures|Flagellar protein 3D structures]] | ||
*[[The Bacterial Flagellar Hook|The Bacterial Flagellar Hook]] | *[[The Bacterial Flagellar Hook|The Bacterial Flagellar Hook]] | ||
| - | *[[User:Fadel A. Samatey/FlgE I|User:Fadel A. Samatey/FlgE I]] | ||
| - | *[[User:Fadel A. Samatey/FlgE III/Intrinsically Disordered Flagellar Rod Stretch|User:Fadel A. Samatey/FlgE III/Intrinsically Disordered Flagellar Rod Stretch]] | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: DeRosier | + | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium]] |
| - | [[Category: Imada | + | [[Category: DeRosier DJ]] |
| - | [[Category: Kitao | + | [[Category: Imada K]] |
| - | [[Category: Matsunami | + | [[Category: Kitao A]] |
| - | [[Category: Nagashima | + | [[Category: Matsunami H]] |
| - | [[Category: Namba | + | [[Category: Nagashima S]] |
| - | [[Category: Samatey | + | [[Category: Namba K]] |
| - | [[Category: Shaikh | + | [[Category: Samatey FA]] |
| - | [[Category: Thomas | + | [[Category: Shaikh TR]] |
| - | + | [[Category: Thomas DR]] | |
| - | + | ||
Current revision
Crystal structure of FlgE31, a major fragment of the hook protein
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