7jw6
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Drosophila Nibbler EXO domain== | |
| - | + | <StructureSection load='7jw6' size='340' side='right'caption='[[7jw6]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7jw6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JW6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JW6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jw6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jw6 OCA], [https://pdbe.org/7jw6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jw6 RCSB], [https://www.ebi.ac.uk/pdbsum/7jw6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jw6 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MUT7_DROME MUT7_DROME] Possesses 3'-5' exoribonuclease activity. Required for 3'-end trimming of AGO1-bound miRNAs, in particular multiple-isoform miRNAs, which represents a critical step in miRNA maturation.<ref>PMID:22055292</ref> <ref>PMID:22055293</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Drosophila melanogaster]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ameres SL]] | ||
| + | [[Category: Brennecke J]] | ||
| + | [[Category: Hayashi R]] | ||
| + | [[Category: Patel DJ]] | ||
| + | [[Category: Sowemimo I]] | ||
| + | [[Category: Wang J]] | ||
| + | [[Category: Xie W]] | ||
Current revision
Crystal structure of Drosophila Nibbler EXO domain
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