RING box protein

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== 3D Structures of RING box protein ==
== 3D Structures of RING box protein ==
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[[Ring box protein 3D structures]]
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*Ring box protein 1
 
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**[[2lgv]] – hRBX1 residues 12-108 (mutant) – human - NMR <br />
 
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**[[1ldj]] – hRBX1 + hCullin-1 <br />
 
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**[[3rtr]] – hRBX1 + hCullin-1 residues 411-766 (mutant) <br />
 
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**[[1ldk]] – hRBX1 + hCullin-1 + cyclin A/Cdk2-asociated protein + Skp2-like protein <br />
 
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**[[1u6g]] – hRBX1 + hCullin-1 + TIP120 protein <br />
 
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**[[4f52]] – hRBX1 + hCullin-1 residues 411-690 (mutant) + glomulin<br />
 
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**[[4p5o]] – hRBX1 + hCullin-1 residues 411-776 + Dcn1-like protein + NEDD8-conjugating enzyme Ubc12 + NEDD8-conjugating enzyme Ubc12 + NEDD8 <br />
 
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**[[5n4w]] – hRBX1 + hCullin-2 + VHL + elongin B + elongin C <br />
 
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**[[2hye]] – hRBX1 + hCullin-4A + DNA damage-binding protein 1 + nonstructural protein <br />
 
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**[[4a0k]] – hRBX1 + hCullin-4A + DNA damage-binding protein 1 + DNA damage-binding protein 2 + DNA<br />
 
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**[[3dpl]] – hRBX1 + hCullin-5 residues 401-780 (mutant) <br />
 
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**[[3dqv]] – hRBX1 + hCullin-5 residues 401-780 (mutant) + NEDD8 <br />
 
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**[[4a0c]] – hRBX1 + hCullin-4B residues 192-913 + Cullin-associated NEDD8-dissociated protein <br />
 
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**[[4a0l]] – hRBX1 + hCullin-4B + DNA damage-binding protein 1 + DNA damage-binding protein 2 + DNA<br />
 
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**[[6r6h]] – hRBX1 in signalosome – Cryo EM <br />
 
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*Ring box protein 2
 
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**[[2ecl]] – hRBX2 RING domain - NMR <br />
 
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**[[6v9i]] – hRBX2 + cullin5 – Cryo EM <br />
 
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}}
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Human RING finger protein 1 (green) complex with cullin-1 (grey), glomulin (magenta) and Zn+2 ions (grey) (PDB code 4f52)

Drag the structure with the mouse to rotate

3D Structures of RING box protein

Ring box protein 3D structures

References

  1. Jia L, Bickel JS, Wu J, Morgan MA, Li H, Yang J, Yu X, Chan RC, Sun Y. RBX1 (RING box protein 1) E3 ubiquitin ligase is required for genomic integrity by modulating DNA replication licensing proteins. J Biol Chem. 2011 Feb 4;286(5):3379-86. doi: 10.1074/jbc.M110.188425. Epub 2010, Nov 29. PMID:21115485 doi:http://dx.doi.org/10.1074/jbc.M110.188425
  2. Wang W, Qiu J, Liu Z, Zeng Y, Fan J, Liu Y, Guo Y. Overexpression of RING box protein-1 (RBX1) associated with poor prognosis of non-muscle-invasive bladder transitional cell carcinoma. J Surg Oncol. 2013 Jun;107(7):758-61. doi: 10.1002/jso.23317. Epub 2013 Apr 23. PMID:23609182 doi:http://dx.doi.org/10.1002/jso.23317
  3. Wei D, Sun Y. Small RING Finger Proteins RBX1 and RBX2 of SCF E3 Ubiquitin Ligases: The Role in Cancer and as Cancer Targets. Genes Cancer. 2010 Jul;1(7):700-7. doi: 10.1177/1947601910382776. PMID:21103004 doi:http://dx.doi.org/10.1177/1947601910382776

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