7jxg
From Proteopedia
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<StructureSection load='7jxg' size='340' side='right'caption='[[7jxg]]' scene=''> | <StructureSection load='7jxg' size='340' side='right'caption='[[7jxg]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full | + | <table><tr><td colspan='2'>[[7jxg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JXG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JXG FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jxg OCA], [https://pdbe.org/7jxg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jxg RCSB], [https://www.ebi.ac.uk/pdbsum/7jxg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jxg ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MTND_HUMAN MTND_HUMAN] Catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line.[HAMAP-Rule:MF_03154]<ref>PMID:11602742</ref> <ref>PMID:15938715</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Dioxygenase 3D structures|Dioxygenase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Deshpande A]] | [[Category: Deshpande A]] | ||
Current revision
Structural model for Fe-containing human acireductone dioxygenase
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Categories: Homo sapiens | Large Structures | Deshpande A | Garber A | Liu X | Pochapsky TC | Ringe D | Ryan J
