Progestogens

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(New page: <StructureSection load='2w8y' size='350' side='right' caption='Structure of human progesterone receptor ligand-binding domain complex with RU486 and sulfate (PDB entry 2w8y)' scene='78...)
Current revision (13:57, 14 November 2021) (edit) (undo)
 
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<StructureSection load='2w8y' size='350' side='right' caption='Structure of human progesterone receptor ligand-binding domain complex with RU486 and sulfate (PDB entry [[2w8y]])' scene='78/780972/Cv/2'>
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<StructureSection load='2w8y' size='300' side='right' caption='Structure of human progesterone receptor ligand-binding domain complex with RU486 and sulfate (PDB entry [[2w8y]])' scene='78/780972/Cv/2'>
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This is a default text for your page '''Progestogens'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
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'''Progesterone'''
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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
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== Function ==
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<scene name='89/895670/Cv/7'>Progesterone</scene> (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.
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*[[Progesterone receptor]]. <scene name='89/895670/Cv/8'>Human progesterone receptor ligand-binding domain bound with progesterone</scene> ([[1a28]]). Water molecules are shown as red spheres.
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== Disease ==
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*Progesterone is a negative allosteric modulator of [[nicotinic acetylcholine receptors]], and a potent antagonist of the [[mineralocorticoid receptor]].
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== Relevance ==
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*[[Hydroxysteroid dehydrogenase]], 20-α HSD is involved in the control of progesterone level in pregnancy of mice. 17-β HSD is involved in the conversion of androstenedione to testosterone.
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== Structural highlights ==
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
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</StructureSection>
</StructureSection>
== References ==
== References ==
<references/>
<references/>

Current revision

Structure of human progesterone receptor ligand-binding domain complex with RU486 and sulfate (PDB entry 2w8y)

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References

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky

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