8fr5
From Proteopedia
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(New page: '''Unreleased structure''' The entry 8fr5 is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the Human Smacovirus 1 Rep domain== | |
| + | <StructureSection load='8fr5' size='340' side='right'caption='[[8fr5]], [[Resolution|resolution]] 1.33Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[8fr5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_smacovirus_1 Human smacovirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FR5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FR5 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.33Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8fr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8fr5 OCA], [https://pdbe.org/8fr5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8fr5 RCSB], [https://www.ebi.ac.uk/pdbsum/8fr5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8fr5 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A0B5CMT4_9VIRU A0A0B5CMT4_9VIRU] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Replication initiator proteins (Reps) from the HUH endonuclease family process specific single-stranded DNA sequences to initiate rolling-circle replication in viruses. Here, the first crystal structure of the apo state of a Rep domain from the smacovirus family is reported. The structure of the human smacovirus 1 Rep domain was obtained at 1.33 A resolution and represents an expansion of the HUH endonuclease superfamily, allowing greater diversity in bioconjugation-tag applications. | ||
| - | + | The crystal structure of the human smacovirus 1 Rep domain.,Limon LK, Shi K, Dao A, Rugloski J, Tompkins KJ, Aihara H, Gordon WR, Evans RL 3rd Acta Crystallogr F Struct Biol Commun. 2023 Dec 1;79(Pt 12):295-300. doi: , 10.1107/S2053230X23009536. Epub 2023 Dec 5. PMID:38051309<ref>PMID:38051309</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 8fr5" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Human smacovirus 1]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Aihara H]] | ||
| + | [[Category: Dao A]] | ||
| + | [[Category: Evans IIII RL]] | ||
| + | [[Category: Gordon WR]] | ||
| + | [[Category: Limon LK]] | ||
| + | [[Category: Rugloski J]] | ||
| + | [[Category: Shi K]] | ||
| + | [[Category: Tompkins KJ]] | ||
Current revision
Crystal structure of the Human Smacovirus 1 Rep domain
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Categories: Human smacovirus 1 | Large Structures | Aihara H | Dao A | Evans IIII RL | Gordon WR | Limon LK | Rugloski J | Shi K | Tompkins KJ
